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Skip to Search Results- 4Genome-wide association study
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Looking beyond the standard genome-wide association study: Biologically-motivated methodological approaches to discover novel genetic variants associated with complex human traits and disease
DownloadFall 2018
The standard approach for testing associations between common single nucleotide genetic variants (referred to as single nucleotide polymorphisms or SNPs) and disease entails testing disease associations for each SNP in the genome individually. This “hypothesis-free” approach has identified...
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Improving Accuracy of Genomic Prediction for Economically Important Traits in Canadian Holstein Dairy Cattle
DownloadSpring 2017
Milk is a valuable source of energy, high quality protein, and several key minerals and vitamins for humans. Selection for milk production in dairy cattle was first based on phenotype and pedigree information and the knowledge of genetic parameters for the trait of interest. However, substantial...
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Spring 2016
Polar bears (Ursus maritimus) were among the first large mammals to be assessed for genetic variation in the wild, and they remain a common subject of genetics studies. Although recent advances in genotyping technology have allowed for more accurate determination of population structure and the...
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Fall 2013
Breast cancer is the most common cancer among women in the developed world. The disease results from the combined effects of genetic, environmental, reproductive and lifestyle risk factors. Germline DNA variations identified thus far by linkage and genome-wide association studies (GWASs) account...
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Environmental biosafety of field scale GM triticale (xTriticosecale Wittmack) cultivation for bioindustrial applications
DownloadSpring 2012
Triticale (xTriticosecale Wittmack) is an intergeneric hybrid of wheat (Triticum aestivum L. and T. Durum Desf.) and rye (Secale cereale L.) that is primarily utilized as an animal feed crop, but is being genetically modified (GM) to take advantage of its bioindustrial qualities. Prior to release...
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Environmental biosafety of genetically engineered crops: Flax (Linum usitatissimum L.) as a model system
DownloadSpring 2010
Flax (Linum usitatissimum L.) is considered as a model plant species for multipurpose uses with whole plant utilization for several purposes including industril, food, animal feed, fiber, nutraceutical, pharmaceutical, and bioproduct markets. Therefore, flax is in the process of genetic...