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- 3Gastrointestinal Tract
- 2Inflammatory Bowel Disease
- 1Antunes, L. Caetano M.
- 1Croxen, Matthew A.
- 1Dicksved, Johan
- 1Dieleman, Levinus A.
- 1Ferreira, Rosana B.
- 1Finlay, B. Brett
The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonizationDownload
The intestinal microbiota is composed of hundreds of species of bacteria, fungi and protozoa and is critical for numerous biological processes, such as nutrient acquisition, vitamin production, and colonization resistance against bacterial pathogens. We studied the role of the intestinal...
Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunctionDownload
Treatment with the probiotic bacterium Lactobacillus reuteri has been shown to prevent dextran sodium sulfate (DSS)-induced colitis in rats. This is partly due to reduced P-selectin-dependent leukocyte- and platelet-endothelial cell interactions, however, the mechanism behind this protective...
Chemically defined diet alters the protective properties of fructo-oligosaccharides and isomalto-oligosaccharides in HLA-B27 transgenic ratsDownload
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but it remains unclear whether microbiota changes mediate their colitis-modulating effects. This study assessed intestinal microbiota and intestinal inflammation after feeding chemically defined...