Search
Skip to Search Results- 1Adams, Scott C
- 1Alabi, Adekunle
- 1Aldana Hernandez, Paulina
- 1Azad, Abul K
- 1Darvesh, Nazia
- 1Haave Audet, Elene
- 3Department of Agricultural, Food, and Nutritional Science
- 2Department of Biological Sciences
- 2Physical Education and Recreation
- 1Department of Agricultural, Food and Nutritional Science
- 1Department of Biochemistry
- 1Department of Medicine
- 2Proctor, Spencer (Agricultural, Food and Nutritional Science)
- 1Baksh, Shairaz (Pedritics)
- 1Boutin, Stan (Biological Sciences)
- 1Carson, Valerie (Physical Education and Recreation); Spence, John C. (Physical Education and Recreation)
- 1Courneya, Kerry (Physical Education and Recreation)
- 1Davidge, Sandra T (Ob/Gyn, Physiology)
-
Spring 2023
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality worldwide. Long-term elevated plasma levels of low-density lipoprotein cholesterol (LDL-C) are the major risk factors for developing atherosclerotic lesions, which can eventually lead to myocardial...
-
Spring 2023
Atherosclerosis and aortic aneurysms are two major vascular diseases, and extracellular matrix (ECM) plays an important role in both as a non-cellular component of the aortic wall that also regulates vascular cell behavior and function. Atherosclerosis is a major contributor to cardiovascular...
-
Spring 2022
Carotid atherosclerosis is responsible for 15-25% of the nearly 8 million first-ever ischemic strokes that occur each year worldwide. This proportion has remained constant over the past three decades, thus suggesting that some patients with carotid atherosclerosis currently receive suboptimal...
-
Insights into Membrane Type-1 Matrix Metalloproteinase cleavage of the Low-density Lipoprotein Receptor
DownloadSpring 2021
The Low-density lipoprotein receptor (LDLR) mediated cellular uptake of LDL is the main pathway for plasma LDL cholesterol (LDL-C) clearance. However, the LDLR can be proteolytically cleaved to release its soluble ectodomain (sLDLR) into the extracellular milieu and as such reducing its LDL-C...
-
Fall 2021
Choline, as an essential nutrient, is needed for a variety of biological processes such as phospholipid synthesis, cell-membrane signaling, lipoprotein secretion, acetylcholine biosynthesis, and one-carbon metabolism. In the North American population diet the two most common forms of choline in...
-
Fall 2021
The field of animal personality, the study of adaptive among-individual behavioural differences in animal populations, has both exploded in popularity in the last few decades and come under heavy scrutiny by behavioural ecologists. The sudden interest in the field stems from the widespread...
-
Fall 2017
Phosphatidylethanolamine N-methyltransferase (PEMT) is a hepatic enzyme that converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/- mice are protected from obesity and insulin resistance, a phenotype that is reversed with dietary choline supplementation. Additionally, PEMT deficiency...
-
Effects of High-Intensity Aerobic Interval Training on Cardiovascular Disease Risk and Health-related Quality of Life in Testicular Cancer Survivors: The HIITTS Trial
DownloadFall 2017
Background: Testicular cancer (TC) survivors (TCS) are an understudied, high-risk group susceptible to late-onset treatment-related cardiovascular disease (CVD), psychosocial, and health-related quality of life (HRQoL) deficits in the years following treatment. Importantly, despite having the...
-
Resources and Reproductive Trade-offs Affect Fitness, Life History Traits, and Sexual Selection in Red Squirrels
DownloadSpring 2017
Animals face trade-offs throughout life between competing functions, such as between self-maintenance, reproduction, and survival. Resource allocation between these competing functions leads to different patterns of life history traits, changes in investment in reproductive effort, and different...
-
Longitudinal and cross-sectional associations between physical activity, screen time, and fitness in a sample of young children from Edmonton, Canada
DownloadFall 2016
Background: High fitness is associated with several positive health outcomes; however, fitness of Canadian children has declined over the past two decades. Correlates of fitness in children under 10 years of age are relatively unexplored, and few studies involving young children have looked at...