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Skip to Search Results- 1Bechtel, Gregory
- 1Bekkari, Mohamed
- 1Caballero, Hebert S
- 1Chai, Robert Andrew.
- 1Cummins, Jim
- 1Dash, U. N.
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Integrating Characteristics of Executive Functions in Non-Demented Aging: Structure, Trajectories, Classification, and Biomarker Predictors
DownloadSpring 2019
In aging, executive function (EF) performance (level) and change (trajectory) are linked to multiple interacting risk factors. Structurally, EFs have previously been represented as either a unitary (e.g., unidimensional) or diverse (e.g., multidimensional) set of abilities that change across the...
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Surrogate markers of progression in Parkinson disease: Correlation between clinical features and neuroimaging
DownloadSpring 2015
Parkinson disease is a progressive neurodegenerative disorder affecting approximately 100,000 Canadians. Loss of dopaminergic neurons in the substantia nigra of the basal ganglia is the prominent pathology associated with many of the motor features that characterise Parkinson disease. Increased...
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Fall 2017
NPAS3 encodes a transcription factor of the bHLH-PAS family, which has been robustly associated with neurodevelopmental and psychiatric disorders with intellectual disability as a common feature. NPAS3 was initially discovered as a schizophrenia-associated gene in a family with a translocation...
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Neural Correlates of Emotion-Cognition Interactions in Healthy Functioning and Adolescent Psychopathology
DownloadFall 2015
The current dissertation implemented two large studies involving brain imaging and behavioral methods to expand our current understanding of the impact of emotion on cognition. Study one focused on the immediate and long-term impact of emotion on cognition in healthy functioning. Study two...