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Skip to Search Results- 22Biological Sciences, Department of
- 21Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 7Graduate and Postdoctoral Studies (GPS), Faculty of
- 7Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas
Download2014
McBride, Ryan, Fokin, Valery V., He, Yuan, Macauley, Matthew S., Paulson, James C. , Arlian, Britni M., Rillahan, Cory D., Rangarajan, Janani, Schwartz, Erik
The siglec family of sialic acid-binding proteins are endocytic immune cell receptors that are recognized as potential targets for cell directed therapies. CD33 and CD22 are prototypical members and are validated candidates for targeting acute myeloid leukaemia and non-Hodgkin's lymphomas due to...
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2007
Berry, K.M., Erickson, T., Callander, D., Koss, R., Ngai, J., Stout, J., Waskiewicz, A.J., Wuennenberg-Stapleton, K., Moens, C.B., Hagey, D.W., French, C.R.
Background Pbx genes encode TALE class homeodomain transcription factors that pattern the developing neural tube, pancreas, and blood. Within the hindbrain, Pbx cooperates with Hox proteins to regulate rhombomere segment identity. Pbx cooperates with Eng to regulate midbrain-hindbrain boundary...
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The APETALA-2-Like Transcription Factor OsAP2-39 Controls Key Interactions between Abscisic Acid and Gibberellin in Rice
Download2010
Rothstein, Steven J., Bi, Yong-Mei, Zhu, Tong, El-kereamy, Ashraf, Beatty, Perrin H., Yaish, Mahmoud W., Good, Allen G.
The interaction between phytohormones is an important mechanism which controls growth and developmental processes in plants. Deciphering these interactions is a crucial step in helping to develop crops with enhanced yield and resistance to environmental stresses. Controlling the expression level...
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Mitogen-activated protein kinase-dependent activation of the na+/H+ exchanger is mediated through phosphorylation of amino acids ser(770) and ser(771)
Download2007-01-01
Malo, Mackenzie E., Li, Liang, Fliegel, Larry
We investigated regulation of the type 1 isoform of the Na+/H+ exchanger by phosphorylation. Four specific groups of serine and threonine residues in the regulatory carboxyl-terminal tail were mutated to alanine residues: group 1, S693A; group 2, T718A and S723A/S726A/S729A; group 3,...
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Tracking and Controlling Persons: Identification for Control in Cognitive Behaviours and Cultural Practices
DownloadFall 2015
This research aims (i) to demonstrate the unity of the phenomena of person identification and control and (ii) to propose the first philosophical theory that uses a single conceptual framework to describe and explain these phenomena. Chapter 1 introduces the philosophical significance of the...
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1995
Abstract: A cluster of genes of the CYP6 family was found in a series of overlapping lambda DASH clones from a genomic library of the house fly, Musca domestica, Four complete genes, CYP6A3, CYP6A4, CYP6A5, and CYP6C1, and fragments of two other genes, CYP6A6 and CYP6C2, were closely linked on a...
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2007
Sperling, F. A. H., MacQuarrie, C. J. K., Langor, D. W.
Mitochondrial cytochrome oxidase I and 11 genes were sequenced for two invasive alien birch (Betula L. [Betulaceae]) leaf-mining sawflies, Profenusa thomsoni (Konow, 1886) (Hymenoptera: Tenthredinidae) and Scolioneura betuleti (King, 1816) (Hymenoptera: Tenthredinidae), accidentally introduced...
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2012
Müller-Reichert, T., Greenan, G., O'Toole, E., Srayko, M., Lange, K.I.
As part of a multi-subunit ring complex, γ-tubulin has been shown to promote microtubule nucleation both in vitro and in vivo, and the structural properties of the complex suggest that it also seals the minus ends of the polymers with a conical cap. Cells depleted of γ-tubulin, however, still...
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Children's Expression of Emotional and Cognitive Mental States in their Story Generation from Pictures
Download2014-05-05
Ortlieb, Andrea, Babar, Aseea, Baird, Shelby, Lang, Bretton
Background: The term mental state can be used to describe a person’s emotional or cognitive condition (i.e. feelings, thoughts, or perceptions). Narratives provide an important context for the use of mental state words, since stories in Western culture frequently describe characters’ thoughts...
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2009
Wishart, D.S., Psychogios, N., Young, N., Xia, J.
Metabolomics is a newly emerging field of ‘omics’ research that is concerned with characterizing large numbers of metabolites using NMR, chromatography and mass spectrometry. It is frequently used in biomarker identification and the metabolic profiling of cells, tissues or organisms. The data...