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Effects of High-Intensity Aerobic Interval Training on Cardiovascular Disease Risk and Health-related Quality of Life in Testicular Cancer Survivors: The HIITTS Trial
DownloadFall 2017
Background: Testicular cancer (TC) survivors (TCS) are an understudied, high-risk group susceptible to late-onset treatment-related cardiovascular disease (CVD), psychosocial, and health-related quality of life (HRQoL) deficits in the years following treatment. Importantly, despite having the...
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Characterization of a novel model of intestinal lipoprotein overproduction and the impact of N-3 PUFA supplementation
DownloadFall 2009
Overproduction of intestinal chylomicrons (CM) has been proposed to contribute to fasting and post-prandial (PP) dyslipidemia and may accelerate the development of cardiovascular disease (CVD) during obesity, insulin resistance (IR) and diabetes. However, the impact of morphological changes in...
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Mental health and chronic medical conditions: schizophrenia, its treatment, risk of metabolic complications, and health care utilization
DownloadFall 2010
Objective - To assess the relationship between schizophrenia and cardiovascular disease by evaluating metabolic risk associated with treatment for schizophrenia, prevalence of cardiovascular risk factors (CV-RF) and disease (CV-D), and health care utilization in people with schizophrenia...
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Spring 2014
Lower-extremity peripheral artery disease (PAD) is a manifestation of atherosclerotic disease in the lower limbs. PAD is a risk factor for poor outcomes including myocardial infarction, stroke, and mortality. Despite the potential benefits of early PAD detection, in the majority of PAD cases...
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Are Sex and Estrogen Modulators of Sympathetic Vascular Control in Resting and Contracting Skeletal Muscle?
DownloadSpring 2018
The purpose of this thesis was to investigate whether sex and estrogen modulate sympathetic neurovascular control in resting and contracting skeletal muscle. This thesis also investigated the hypothesis that the effects of sex and estrogen on neurovascular control would be mediated by the signal...
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Cardiovascular Disease Risk factors in Canadian-born and Immigrant Children and Youth in the Canadian Health Measures Survey
DownloadFall 2014
Immigrants make up almost 20% of Canada’s population. Recent adult immigrants to Canada are generally in better health than those born in Canada. However, we know little about whether this is also the case in children. We compared mean levels and prevalence of adverse levels of CVD risk factors...
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2008
Ambrose, Divakar J., Emmanuel, Daya G. V.
Abstract — An 8-month-old, virgin Holstein heifer with precocious mammary development was presented for examination. Protein, fat, and lactose in the mammary secretion were 14.90%, 0.12%, and 0.20%, respectively; somatic cell count was 3.9 3 10 6 /mL, with no bacterial infection. The heifer was...
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Innovative strategic Canadian research training from TomorrOw’s Research Cardiovascular Health Care Professionals (TORCH).
Download2004
Lopaschuk, G., Ezekowitz, C., Armstrong, P.W., Michelakis, E., Seldon, R., Ghali, W.A., Archer, S., Anderson, T., Jensen, L., Hayward, R.
Cardiovascular research training is experiential, and \"skills\" are traditionally acquired through a master-apprentice paradigm. The complexity of contemporary clinical research requires a new model for research training. Facilitated through a Strategic Training Program Initiative, the Canadian...
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Common Low-Density Lipoprotein Receptor p.G116S Variant Has a Large Effect on Plasma Low-Density Lipoprotein Cholesterol in Circumpolar Inuit Populations
Download2014-11-20
Dubé, Joseph B., Wang, Jian, Cao, Henian, McIntyre, Adam D., Johansen, Christopher T., Hopkins, Scarlett E., Stringer, Randa, Hosseinzadeh, Siyavash, Kennedy, Brooke A., Ban, Matthew R., Young, T. Kue, Connelly, Philip W., Dewailly, Eric, Bjerregaard, Peter, Boyer, Bert B., Hegele, Robert A.
"Background: Inuit are considered to be vulnerable to cardiovascular disease because their lifestyles are becoming more Westernized. During sequence analysis of Inuit individuals at extremes of lipid traits, we identified 2 nonsynonymous variants in low-density lipoprotein receptor (LDLR), namely...
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ECG for high-throughput screening of multiple diseases: Proof-of-concept using multi-diagnosis deep learning from population-based datasets
Download2021
Sun, W., Kalmady, S.V., Salimi, A.S., Sepehrvand, N., Ly, E., Hindle, Abram, Greiner, R., Kaul, P.
Electrocardiogram (ECG) abnormalities are linked to cardiovascular diseases, but may also occur in other non-cardiovascular conditions such as mental, neurological, metabolic and infectious conditions. However, most of the recent success of deep learning (DL) based diagnostic predictions in...