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- 1Adrenomedullin--Physiological effect
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- 1Endothelial progenitor cells
- 1Human placenta
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Existence of endothelial progenitor cells with self-renewal and clonogenic potential in normal human placenta and preeclampsia
DownloadSpring 2013
Preeclampsia (PE) is the leading cause of maternal death in developing countries. PE is defined as hypertension and proteinuria after 20 weeks of gestation. The only curative treatment is placental delivery. Evidence suggests that placental vasculature is disturbed with shallow invasion of...
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The Role of Matrix Metalloproteinase-2 in the Pathophysiology of a Reduced Utero-Placental Perfusion Pressure Model of Preeclampsia
DownloadFall 2012
Preeclampsia is a leading cause of maternal and fetal morbidity/mortality and induced preterm birth. Endothelin-1 (ET-1) is a potent vasoactive agent, shown to be involved in the vascular endothelial dysfunction of preeclampsia. Big endothelin (bigET) is cleaved to ET-1 by several enzymes...
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Spring 2016
Preeclampsia, defined as new-onset hypertension after 20 weeks of gestation with concurrent proteinuria, is the leading cause of maternal mortality. Preeclampsia is a multi-system disorder with serious maternal and fetal morbidities, which affects 2 – 8% of pregnancies worldwide. Although the...