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- 2Al Sayah, Fatima
- 1Adame Perez, Stephany
- 1Al-Adra, David P.
- 1Albalawi, Zaina H
- 1Anderson, Sarah J
- 1Asaad, Ghada A
- 7Department of Agricultural, Food, and Nutritional Science
- 5Department of Surgery
- 3Faculty of Pharmacy and Pharmaceutical Sciences
- 3School of Public Health
- 2Department of Medical Microbiology and Immunology
- 2Department of Medicine
- 2Johnson, Jeff A. (School of Public Health Sciences, University of Alberta)
- 2Williams, Beverly (Faculty of Nursing, University of Alberta)
- 1Anderson, Colin (Medical Microbiology and Immunology and Surgery)
- 1Baldwin, Troy (Medical Microbiology and Immunology)
- 1Chan, Catherine (Agricultural, Food and Nutritional Sciences)
- 1Dr. Scot Simpson (Faculty of Pharmacy and Pharmaceutical Sciences)
Characterization of Human Pancreatic Beta-cell Progenitors as a Means to Alleviate the Shortage of Donor Tissue for Islet TransplantationDownload
The current shortage of islet tissue from cadaveric human donors is not sustainable and will preclude islet transplantation from becoming a widespread therapeutic treatment for those with type 1 diabetes. A potential alternative source of tissue may be through isolating, expanding, and...
Vitamin D Supplementation and Bone Health in Adults with Diabetic Nephropathy: Preliminary Findings from a Randomized Controlled TrialDownload
Vitamin D (vitD) is a nutrient of concern in Canada particularly for those with diabetes and chronic kidney disease (CKD). Participants (18-80y) with diabetes and CKD were randomized to receive either 50mcg/day (n=33) or 1,000mcg/month (n=30) vitD3 for 6-months. Variables studied included:...
Vitamin D Status and Health-care Outcomes in an Ambulatory Population of Patients with Diabetes and Chronic Kidney disease: A Five-year Follow-up.Download
Vitamin D (VitD) deficiency is a prevalent condition in Canada, especially in northern latitudes where sunlight exposure is limited. Elderly patients especially those with chronic conditions such as Diabetes Mellitus (DM) and Chronic Kidney Disease (CKD) have a higher risk of developing vitD...
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...
Best practices: does it mean the same thing in the Aboriginal community as it does in the health authorities when it comes to diabetes care?Download
Best Practices: Does it mean the same thing in the Aboriginal community as it does in the Health Authorities when it comes to diabetes care?
There is a general agreement that a relationship exists between health literacy (HL) and health outcomes. Nonetheless, there are critical gaps in the measurement of HL and in the evidence on the impact of inadequate HL on health outcomes, especially in the diabetes population. These gaps need to...
Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with DiabetesDownload
While guidelines for seasonal influenza vaccinations single out working age (< 65) adults with diabetes, vaccination rates in this group remain below national targets. Historically, there has been limited evidence to support these guidelines. This dissertation comprises four studies investigating...
Establishing mixed hematopoietic chimerism is a promising approach to develop donor-specific tolerance to transplanted organs. Establishing tolerance may eliminate the need for long-term immunosuppressive therapy, prevent chronic rejection and in the case of Type 1 Diabetes (T1DM), reverse...
Islet transplantation has the potential to be an effective treatment for patients with type 1 diabetes. However, a shortage of human donor islets and the need for continuous immunosuppressive therapy currently limit this therapy to patients with brittle type 1 diabetes. Neonatal pigs may...