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Skip to Search Results- 17Graduate and Postdoctoral Studies (GPS), Faculty of
- 17Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 16Chemistry, Department of
- 16Chemistry, Department of/Journal Articles (Chemistry)
- 12Biological Sciences, Department of
- 12Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4Department of Chemistry
- 3Department of Biochemistry
- 3Department of Electrical and Computer Engineering
- 3Department of Mechanical Engineering
- 2Department of Renewable Resources
- 1Department of Biological Sciences
- 2Tang, Tian (Mechanical Engineering)
- 1Cowie, Martin (Chemistry)
- 1Dew, Steven (Electrical & Computer Engineering)
- 1Dew, Steven K (Electrical and Computer Engineering)
- 1Dr. Cindy Paszkowski (Department of Biological Sciences) / Dr. David Coltman (Department of Biological Sciences)
- 1Fleck, Brain (Mechanical Engineering)
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2016
Klassen, John S., Campuzano, Iain D. G., Bagal, Dhanashri, Privé, Gilbert G., Kitova, Elena N., Xiong, Zi Jian, Richards, Michele R., Li, Jun
Saposin A (SapA) lipoprotein discs, also known as picodiscs (PDs), represent an attractive method to solubilize glycolipids for protein interaction studies in aqueous solution. Recent electrospray ionization mass spectrometry (ESI-MS) data suggest that the size and composition of...
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Screening oligosaccharide libraries against lectins using the proxy protein electrospray ionization mass spectrometry assay
Download2016
Privé, Gilbert G., Ng, Kenneth K. S., Xiong, Zi Jian, Klassen, John S., Kitova, Elena N., Fan, Xuxin, Li, Jun, Zou, Chunxia, Eugenio, Luiz, Cairo, Christopher W.
An electrospray ionization mass spectrometry (ESI-MS) assay for screening carbohydrate libraries against lectins is described. The assay is based on the proxy protein ESI-MS method, which combines direct ESI-MS protein–ligand binding measurements and competitive protein binding, to simultaneously...
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Structural variant detection by large-scale sequencing reveals new evolutionary evidence on breed divergence between Chinese and European pigs
Download2016
Liu, Jian-Feng, Fan, Ziyao, Li, Junhui, Wang, Jiafu, Wang, Zhiquan, Zhao, Pengju, Kang, Huimin, Zhang, Qin, Yin, Zongjun, Wang, Haifei
In this study, we performed a genome-wide SV detection among the genomes of thirteen pigs from diverse Chinese and European originated breeds by next genetation sequencing, and constrcuted a single-nucleotide resolution map involving 56,930 putative SVs. We firstly identified a SV hotspot...
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Quantifying labile protein-ligand interactions using electrospray ionization mass spectrometry
Download2010
El-Hawiet, Amr, Liu, Lan, Klassen, John S., Kitova, Elena N.
A new electrospray ionization mass spectrometry (ES-MS) approach for quantifying protein—ligand complexes that are prone to in-source (gas-phase) dissociation is described. The method, referred to here as the reference ligand ES-MS method, is based on the direct ES-MS assay and competitive ligand...
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Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum
Download1990-01-01
Fliegel, Larry, Newton, E., Burns, K., Michalak, M.
A cDNA clone encoding 55-kDa multifunctional, thyroid hormone binding protein of rabbit skeletal muscle sarcoplasmic reticulum was isolated and sequenced. The cDNA encoded a protein of 509 amino acids, and a comparison of the deduced amino acid sequence with the NH2-terminal amino acid sequence...
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1992-01-01
Caceres, J.F., McKenzie, D.I., Thimappaya, R., Lund, E., Dahlberg, J.E.
The expression of mouse embryonic U1 snRNA (mU1b) genes is subject to stage- and tissue-specific control, being restricted to early embryos and adult tissues that contain a high proportion of stem cells capable of further differentiation. To determine the mechanism of this control we have sought...
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Spring 2016
Hybrids formed by biological entities and human-made nano-structures have been intensively studied in recent years due to their very interesting properties and applications. DNA-carbon nanotube (CNT) hybrid is one such material and the motivation of this PhD study. The interaction of DNA building...
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Fall 2014
Developing a simple, general, and isothermal self-replicating system is one of the key requirements for a simplified detection platform for nucleic acid sequences specific to a disease causing microrganism. One of the challenges in achieving nucleic-acid templated isothermal amplification is that...
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Using Biomolecular Recognition to Selectively Self-Assemble Microscale Components onto Patterned Substrates
DownloadSpring 2015
Modern nanofabrication technology in the 21st century has continued year after year to push the boundaries of what is possible at the nanoscale. With the advent of molecular electronics, single electron devices, nanoelectromechanical systems (NEMS), and other nanotechnologies, the near future...
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Fall 2014
Electrons, the fundamental charge carriers in solid-state devices, possess three intrinsic properties: mass, charge and spin. Spin is a quantum mechanical property, but can be loosely visualized as a tiny “intrinsic” magnetic dipole moment attached to an electron. In conventional electron...