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Skip to Search Results- 12Graduate and Postdoctoral Studies (GPS), Faculty of
- 12Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 6Biological Sciences, Department of
- 6Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 3Mathematical and Statistical Sciences, Department of
- 3Mathematical and Statistical Sciences, Department of/Research Publications (Mathematical and Statistical Sciences)
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Temporal dynamics of plant-soil feedbacks and community consequences during Bromus inermis invasion
DownloadSpring 2021
Invasive plant species often come to dominate the community where they have become introduced, posing a serious threat to plant diversity and ecosystem functions. Yet, the long-term dynamics and impacts of invasive species do not necessarily remain constant and may attenuate over time due to...
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The Drivers of Invasive Species Establishment and Impact on Ecological and Evolutionary Aspects of Resident Plant Communities
DownloadSpring 2017
Invasive species can have important ecological and evolutionary impacts on resident species. Yet, we still lack a broad understanding of the conditions that determine invasive species establishment, performance and impact on ecological and evolutionary aspects of communities. In this thesis, I...
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Deciphering the molecular mechanisms underlying the pathobiology of esophageal squamous cell carcinoma
DownloadFall 2015
Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers worldwide, largely due to a high frequency of tumor invasion/metastasis, chemoresistance and recurrence. In this study, we explored from different perspectives the molecular mechanisms behind these aggressive features of...
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Proliferative Signals Regulate Hemocyte Development and Intestinal Immunity in Drosophila melanogaster.
DownloadSpring 2015
The innate immune system is an ancient line of resistance against intrusive microbial threats. This system integrates cellular, humoral, and barrier defenses to generate a protective immune response. These divisions are indispensable and conserved between Drosophila and mammals. Hemocytes are the...
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The genetic signature of rapid range expansions: How dispersal, growth and invasion speed impact heterozygosity and allele surfing
Download2014-01-01
Lewis, Mark A. , Coltman, David W. , Goodsman, Devin W., Cooke, Barry
As researchers collect spatiotemporal population and genetic data in tandem, models that connect demography and dispersal to genetics are increasingly relevant. The dominant spatiotemporal model of invasion genetics is the stepping-stone model which represents a gradual range expansion in which...
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Fall 2013
Species invasions are increasing worldwide and are impacting populations, communities, and ecosystems. Non-native species that are ecosystem engineers, such as earthworms, may be particularly likely to have large impacts due to their ability to modify both biological and physical characteristics...
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Novel Insights into the Role of O6-Methylguanine-DNA Methyltransferase in Glioblastoma Angiogenesis, Invasion, and Proliferation
DownloadFall 2012
Glioblastoma multiforme (GBM) is characterized by aberrant angiogenesis, rapid proliferation, and widespread invasion through the brain parenchyma. Thus, the prognosis for these tumors remains extremely poor despite aggressive multimodal treatment including chemotherapy with the alkylating agent...
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The role of endothelial PI3 kinase activity and IQGAP1 in regulation of lymphocyte diapedesis
DownloadFall 2011
Leukocyte extravasation is a fundamental process of the inflammatory responses. The mechanisms that control remodelling of endothelial (EC) shape and adhesive contacts during leukocyte transendothelial migration (TEM) are not completely understood. We studied the role of EC phosphatidylinositol...
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Mechanisms regulating Poa pratensis L. and Festuca campestris Rybd. within the foothills fescue grasslands of southern Alberta
DownloadFall 2011
Invasion of non-native species such as Poa pratensis L. has become a serious threat to the conservation of bunch grass communities including foothills fescue grasslands in Alberta, Canada. Conservation efforts are currently limited by a poor understanding of the ecological mechanisms responsible...
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2006-01-01
McCauley, E., Lewis, Mark A., Lutscher, F.
The question how aquatic populations persist in rivers when individuals are constantly lost due to downstream drift has been termed the “drift paradox.” Recent modeling approaches have revealed diffusion-mediated persistence as a solution. We study logistically growing populations with and...