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Skip to Search Results- 1Afshar, Shima
- 1Arora, Nitin
- 1Chen, Huanchen
- 1Chini, Seyed Farshid
- 1Darius, Juan
- 1Dechaine, Greg Paul
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Tau seeding in a HEK cell model is influenced by aggregation inducers and cellular chaperones
DownloadFall 2022
The tau protein is a microtubule associated protein whose misfolding and subsequent aggregation have been associated with a group of neurodegenerative diseases known as tauopathies. Studying tau in a lab setting has been crucial for the advancement of knowledge and technology used to treat people...
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Spring 2011
Aggregating performance measures considerably reduces the complexity of a performance evaluation system. This dissertation analyzes the nature and characteristics of the aggregation of performance measures in institutional settings of multiple tasks and multiple periods. In multi-task settings,...
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Studying Structure-Nanoaggregation Relations of Polyaromatic Molecules in the Bulk Oil Phase and at the Oil-Water Interface Using Molecular Dynamics Simulation
DownloadSpring 2014
The detection, identification and characterization of early stage molecular association of polyaromatic molecules into nanoaggregates, where these nanoaggregates represent the first level of molecular clusters or building blocks are critical in areas such as design and fabrication of advanced 3-D...
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Spring 2010
Most crude oils contain traces of vanadyl porphyrins within their asphaltene fraction. Although these metals are only present in trace quantities, they have a significant detrimental impact on crude oil processing units; therefore, their selective removal is highly desirable. The current work...
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Fall 2013
Protein folding involves a stochastic search through the configurational energy landscape towards the native structure. Although most proteins have evolved to fold efficiently into a unique native structure, misfolding (the formation of non-native structures) occurs frequently in vivo causing a...
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Spring 2014
Introduction of a binding or reacting liquid into a gas-solid fluidized bed is common in industrial processes (e.g. fluid coking, catalytic cracking, granulation). Ability of the liquid to spread and the attractive effect on particles due to liquid bridge formation alter the fluidization behavior...
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Rheology of Bitumen at the Onset of Asphaltene Aggregation and its Effects on the Stability of Water-in-Oil Emulsion
DownloadFall 2015
Asphaltenes are the heaviest fraction of bitumen. Asphaltenes not only play an important role in the high viscosity of bitumen but also in the water-in-oil (W/O) emulsion stability. Nevertheless, their exact function in the stability mechanism of W/O emulsion still remains unresolved. It is...
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Fall 2018
The production of a tailings waste stream is ubiquitous to mining and mineral processing operations, especially in Alberta’s oil sands industry. Due to the presence of colloidal clays such as kaolinite, which do not naturally sediment in suspension, water recycling and land reclamation remain...
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Molecular Dynamics Investigation on the Aggregation of Polyaromatic Compounds in Water and Organic Solvents
DownloadFall 2015
Aggregation of polyaromatic (PA) compounds has drawn great interest due to their wide impacts in areas such as petroleum processing. Despite the extensive studies on PA compounds, fundamental knowledge of their aggregation behaviors is still missing at atomistic level. For instance, it’s still...
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Mechanisms of Aggregation and Separation of Water and Solids from Bitumen Froth using Cluster Size Distribution
DownloadFall 2016
The large-scale corrosion and equipment damage caused by water and solids respectively in bitumen froth necessitate their removal using various methods. This study is aimed at understanding how water and solids aggregate (water-water, water-solid and solid-solid) in bitumen froth and what the...