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Skip to Search Results- 1Ajamian, Farnam
- 1Archibald, Mandy M
- 1Aung, Yin N
- 1Bahreinian, Salma
- 1Elamy, Abdel-Halim H
- 1Ethier, Caroline D
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Sensitivity of Ambient NO2 Concentration to Upstream Oil and Gas and Transportation Emissions in Alberta
DownloadFall 2023
Ambient exposure to nitrogen dioxide (NO2) and ozone (O3) is associated with severe health problems and health-related economic burdens. The levels of NO2 concentration in the province of Alberta show that they will exceed the updated Canadian Ambient Air Quality Standards (CAAQS) in Edmonton and...
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An Exploration of the Associations Between Gut and Serum Immunoglobulin A in Infancy and Asthma in Childhood
DownloadSpring 2020
Introduction Early immune maturation and gut microbial composition have a clear impact on the development of asthma and atopy in children. There is a large body of evidence on the association between immunoglobulin A (IgA), asthma, and other atopic diseases. Low secretory Immunoglobulin A (sIgA)...
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Mapping intracellular cytokine pools in granulocytes: Dynamic storage and trafficking sites of interleukin-9 and interleukin-13 in human eosinophils
DownloadFall 2020
Eosinophils are immune cells with constantly evolving roles in both innate and adaptive immunity and have long been associated with the predominant pathology of the human airways, asthma. Eosinophils are specialized in their granulocytic nature, possessing several membrane-bound secretory...
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Spring 2018
Introduction: Asthma is a chronic inflammatory disease characterized by intermittent episodes of acute airway inflammation and bronchoconstriction. Although asthma is generally considered a disease of the airways, asthma is also associated with an increased risk of developing cardiovascular (CV)...
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An Analysis of the Environmental Risk Factors of Childhood Asthma and Asthma-like Symptoms: Results from the National Longitudinal Survey of Children and Youth
DownloadSpring 2016
It is known that a multitude of environmental factors are implicated in the incidence of asthma and asthma symptoms among children; however, previous research has provided inconsistent and/or insufficient evidence as to whether residing in a farming environment during childhood can lead to a...
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Developing a Patient-Driven Arts-Based Knowledge Translation Tool for Parents of Children with Asthma
DownloadSpring 2016
Background: Family-centered education is critical to managing childhood asthma, the most common chronic disease of childhood in North America. Parents are largely responsible for the day-to-day management of their child’s asthma; as such, finding effective ways to educate parents about asthma is...
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Outdoor Air Pollution and Children´s Asthma in the Census Metropolitan Area of Edmonton, Alberta: the Influence of Place of Residence and Socioeconomic Position
DownloadFall 2016
Background: Asthma is the most common chronic respiratory disease in children and air pollution has been implicated in its development and exacerbations worldwide. The Census Metropolitan Area of Edmonton (CMAE), Alberta, has unique air pollution sources (traffic and industrial related air...
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Fall 2014
Epidemiological studies correlate vitamin D deficiency with asthma severity. Calcitriol modulates receptor and cytokine expression from various leukocytes in an anti-inflammatory manner. Despite eosinophil activity during mucosal inflammation, knowledge on the direct effect of calcitriol on this...
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Spring 2014
Inconsistent results have been reported in studies investigating the relationship between serum vitamin D levels and respiratory outcomes. In this thesis, data from the Canadian Health Measures Survey were used to examine the relationship between serum 25-hydroxy vitamin D [25(OH)D] levels and...