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- 7Single nucleotide polymorphisms
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Quantitative trait loci affecting Rous Sarcoma Virus induced tumor regression trait in F2 intercross chickens
Download2009
Uemoto, Y., Mitsuhashi, T., Saburi, J., Miyata, T., Suzuki, K., Odawara, S., Yamashita, H., Yamamoto, R., Sato, S-I., Plastow, G., Kobayashi, E., Irina, C., Ohtake, T.
We performed a genome-wide linkage and quantitative trait locus (QTL) analysis to confirm the existence of QTL affecting Rous Sarcoma Virus (RSV) induced tumor regression, and to estimate their effects on phenotypic variance in an F2 resource population. The F2 population comprised 158 chickens...
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International genetic evaluations for feed intake in dairy cattle through the collation of data from multiple sources
Download2014
Coffey, M. P., Løvendahl, P., Wang, Z., de Haas, Y., Krattenmacher, N., Berry, D. P., Crowley, J. J., Pryce, J. E., Veerkamp, R. F., Weigel, K., Macdonald, K., Spurlock, D.
Feed represents a large proportion of the variable costs in dairy production systems. The omission of feed intake measures explicitly from national dairy cow breeding objectives is predominantly due to a lack of information from which to make selection decisions. However, individual cow feed...
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2010
Clawson,M. L., Wang, Z., Stothard, P., McKay, S., Laegreid, W. W., Williams J. L., Murdoch, B. M., Settles, M., Moore, S. S., Prasad, A.
Background Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. Polymorphisms that alter the prion protein of sheep or humans have been associated with variations in...
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Developing a genome-wide selection model for genetic improvement of residual feed intake and carcass merit in a beef cattle breeding program
Download2012
Lai, S., Plastow, G., Zeng, Z., Li, X., Ma, J., Tang, G., Moore, S., Wang, Z.
Residual feed intake (RFI) and carcass merit (CM) are both complex traits emerging as critical targets for beef genetic improvement. RFI and CM traits are difficult and expensive to measure and genetic improvement for these traits through traditional selection methods is not very effective....
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2011
Wang, Z., MacNeil, J. D., Stewart-Smith, J., Tang, G., Basarab, J. A., Moore, S. S., Plastow, G.
Crossbreeding is an effective method for improving the efficiency of production in commercial cow-calf operations. It exploits available heterosis (hybrid vigour) and complementarity between different breeds or populations (lines). Before adopting a crossbreeding system, commercial cattle...
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Impact of Feed Efficiency and Diet on Adaptive Variations in the Bacterial Community in the Rumen Fluid of Cattle
Download2012
Hernandez-Sanabria, E., Goonewardene, L. A., Durunna, O.N., Wang, Z., Moore, S S., Guan, L. L.
Limited knowledge of the structure and activities of the ruminal bacterial community prevents the understanding of the effect of population dynamics on functional bacterial groups and on host productivity. This study aimed to identify particular bacteria associated with host feed efficiency in...
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A Simple Polymerase Chain Reaction-based Method for the Discrimination of Three Chicken Breeds
Download2009
Mitsuhashi, T., Kubo, Y., Plastow, G.
A large number of branded chicken products exist in Japan, and in some cases, the breed of chicken is an important factor used to attract consumer interest in the retail product. In order to establish a simple method for verifying such breed claims we applied the amplified fragment length...
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An Assessment of Population Structure in Eight Breeds of Cattle Using a Whole Genome SNP Panel
Download2008
Schnabel, R. D., Wang, Z., Taylor, J. F., Gill, C. A., Van Tassell, C. P., Gao, C., Aerts, J., Williams, J. L., Neto, E. D., Murdoch, B. M., Matukumalli, L. K., Coppieters, W., McKay, S. D., Mannenl, H., Crews, D., Moore, S. S.
Background Analyses of population structure and breed diversity have provided insight into the origin and evolution of cattle. Previously, these studies have used a low density of microsatellite markers, however, with the large number of single nucleotide polymorphism markers that are now...
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Candidate genes and biological pathways associated with carcass quality traits in beef cattle
Download2013
Karisa, B. K., Bruce, H. L., Plastow, G. S., Moore, S. S., Thomson, J., Wang, Z.
The objective of this study was to use the candidate gene approach to identify the genes associated with carcass quality traits in beef cattle steers at the University of Alberta Ranch at Kinsella, Canada. This approach involved identifying positional candidate genes and prioritizing them...
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Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene
Download2015
Sällman Almén, M., Liao, X., Stothard, P., Henegar, C., Van Doormaal, B., Rubin, C. -J., Andersson, L., Barsh, G. S., Ito, S., Plastow, G., Wakamatsu, K., Dorshorst, B.
Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant Black (MC1RD) and Recessive Red (MC1Re). A...