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- 29Stothard, Paul
- 8Wishart, David S.
- 5Liao, Xiaoping
- 5Moore, Stephen S.
- 4Shrivastava, Savita
- 3Bao, Hua
PolySearch: A web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolitesDownload
A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe...
Santana, Andre M., Tonhati, Humberto, Greco, Anthony J., Mishra, Bina, Cai, Zhipeng, Kumar, S. T. Bharani, Tantia, Madhu S., Jones, Brittany C., Saradhi, G. Pardha, Miziara, Melissa N., Kumar, M. Aravind, Kochan, Kelli J., Goldammer, Tom, Brunner, Ronald M., Caetano, Alexandre R., Weikard, Rosemarie, Womack, James E., Mathew, Boby, Kumar, Satish, Pelai, Vanderlei A., Filho, Edson A. R., Jeong, Jooha, Prasad, Aparna, Vijh, Ramesh K., Lin, Guohui, Moore, Stephen, Galvao, Stephan R., Mariani, Paola, Grant, Jason R., Stafuzza, Nedenia B., Fornitano, Larissa C., Riggs, Penny K., Stothard, Paul, Amaral, M. Elisabete
Background The recently constructed river buffalo whole-genome radiation hybrid panel (BBURH5000) has already been used to generate preliminary radiation hybrid (RH) maps for several chromosomes, and buffalo-bovine comparative chromosome maps have been constructed. Here, we present the...
Cholangiocellular carcinoma (CCA) of the liver was the target of more interest, recently, due mainly to its increased incidence and possible association to new environmental factors. Somatic mitochondrial DNA (mtDNA) mutations have been found in several cancers. Some of these malignancies contain...
Genome-wide association and genomic prediction of breeding values for fatty acid composition in subcutaneous adipose and longissimus lumborum muscle of beef cattleDownload
Background Identification of genetic variants that are associated with fatty acid composition in beef will enhance our understanding of host genetic influence on the trait and also allow for more effective improvement of beef fatty acid profiles through genomic selection and marker-assisted diet...
Background Continued sequencing efforts coupled with advances in sequencing technology will lead to the completion of a vast number of small genomes. Whole-genome comparisons represent an important part of the analysis of any new genome sequence, as they can provide a better understanding of the...
Characterization of the altered gene expression profile in early porcine embryos generated from parthenogenesis and somatic cell chromatin transferDownload
The in vitro production of early porcine embryos is of particular scientific and economic interest. In general, embryos produced from in vitro Assisted Reproductive Technologies (ART) manipulations, such as somatic cell chromatin transfer (CT) and parthenogenetic activation (PA), are less...
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical) data with comprehensive drug target (i.e. protein) information. The database contains >4100 drug entries including >800 FDA approved small molecule and biotech drugs as well as >3200...
Comparative analysis of two phenotypically-similar but genomically-distinct Burkholderia cenocepacia-specific bacteriophagesDownload
Background Genomic analysis of bacteriophages infecting the Burkholderia cepacia complex (BCC) is an important preliminary step in the development of a phage therapy protocol for these opportunistic pathogens. The objective of this study was to characterize KL1 (vB_BceS_KL1) and AH2...
Genome-wide analysis of the transcriptional response to porcine reproductive and respiratory syndrome virus infection at the maternal/fetal interface and in the fetusDownload
Background Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant pigs can result in congenital infection and ultimately fetal death. Little is known about immune responses to infection at the maternal-fetal interface and in the fetus itself, or the molecular events...
BacMap is an interactive visual database containing fully labeled, zoomable and searchable chromosome maps from more than 170 bacterial (archaebacterial and eubacterial) species. It uses a recently developed visualization tool (CGView) to generate high-resolution circular genome maps from...