Search
Skip to Search Results- 10Photonic Materials
- 10Stimuli-Responsive Polymers
- 7Etalons
- 4Stimuli Responsive Polymers
- 3Optical Sensing
- 2Biosensing
-
2016
Li, Xue, Serpe, Michael J., Gao, Yongfeng
Poly (N-isopropylacrylamide) (pNIPAm)-based hydrogels and hydrogel particles (microgels) have been extensively studied since their discovery a number of decades ago. While their utility seems to have no limit, this feature article is focused on their development and application for sensing small...
-
2013-01-01
Islam, Molla R., Lu, Zhenzhen, Li, Xue, Sarker, Avijeet K., Hu, Liang, Choi, Paul, Li, Xi, Hakobyan, Narek, Serpe, Michael J.
Stimuli-responsive polymers are capable of translating changes in their local environment to changes in their chemical and/or physical properties. This ability allows stimuli-responsive polymers to be used for a wide range of applications. In this review, we highlight the analytical applications...
-
2015-01-01
Li, Xue, Gao, Yongfeng, Serpe, Michael J.
Poly (N‐isopropylacrylamide) (pNIPAm)‐based hydrogels and hydrogel particles (microgels) have been extensively studied since their discovery and “popularization” a few decades ago. While their uses seem to have no bounds, this Feature Article is focused on their development and application for...
-
Reductant responsive poly (N-isopropylacrylamide) microgels and microgel-based optical materials
Download2015-01-01
Li, Xue, Gao, Yongfeng, Serpe, Michael J.
Poly(N-isopropylacrylamide) based hydrogel particles (microgels) crosslinked with N,N′-bis(acryloyl)cystamine were prepared using free-radical precipitation polymerization. By coating a single layer of microgels on a gold-coated glass substrate followed by the addition of another gold layer, an...
-
Polymer-based devices for the label-free detection of DNA in solution: low DNA concentrations yield large signals
Download2014-01-01
Islam, Molla R., Serpe, Michael J.
Poly (N-isopropylacrylamide-co-N-(3-aminopropyl) methacrylamide hydrochloride) microgel-based optical devices (etalons) have been shown to change their optical properties in the presence of single-stranded DNA. We hypothesize that this is due to the negatively charged DNA penetrating through the...
-
2016-01-01
Jiang, Yaxin, Colazo, Marcos G., Serpe, Michael J.
Progesterone (P4) is a vital steroid hormone involved in the reproduction cycle and necessary for maintenance of pregnancy in humans and animals. Monitoring P4 concentrations is required in various fields, such as dairy industry, environmental protection, and clinical laboratories. The current...
-
2014
Ahiabu, Andrews, Islam, Molla R., Li, Xue, Serpe, Michael J.
Responsive polymer-based materials have found numerous applications due to their ease of synthesis and the variety of stimuli that they can be made responsive to. In this review, we highlight the group’s efforts utilizing thermoresponsive poly (N-isopropylacrylamide) (pNIPAm) microgel-based...
-
Poly (N-isopropylacrylamide) microgel-based etalons for the label-free quantitation of estradiol-17β in aqueous solutions and milk samples
Download2018-01-01
Jiang, Yaxin, Colazo, Marcos G., Serpe, Michael J.
A novel estradiol-17β (E2) biosensor was constructed from poly(N-isopropylacrylamide) (pNIPAm) microgel-based etalons by modification of their outermost Au layer with an E2 binding 75-mer DNA aptamer. When E2 is not present in the solution, the aptamer forms a loose/linear structure that allows...
-
2012
Poly (N-isopropylacrylamide) (pNIPAm) is one of the most completely studied “smart” polymers due to its unique reversible thermoresponsivity. That is, when pNIPAm in water is heated > ~31°C, it transits from a random coil to a globule conformation; this transition is reversed when T < ~31°C. This...
-
2015-01-01
Islam, Molla R., Xie, Shuyi, Huang, Danqing, Smyth, Keady, Serpe, Michael J.
Optical sensors for environmental humidity have been constructed from poly (N-isopropylacrylamide)-co-acrylic acid (pNIPAm-co-AAc) microgels. The devices were constructed by first depositing a monolithic layer of pNIPAm-co-AAc microgels on a Au-coated glass substrate followed by the addition of...