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Variation in Fetal Outcome, Viral Load and ORF5 Sequence Mutations in a Large Scale Study of Phenotypic Responses to Late Gestation Exposure to Type 2 Porcine Reproductive and Respiratory Syndrome Virus
Download2014
Plastow, G., Lunney, J. K., Ladinig, A., Ashley, C., Detmer, S. E., Wilkinson, A., Harding, J. C. S.
In spite of extensive research, the mechanisms of reproductive disease associated with Porcine Reproductive and Respiratory Syndrome virus (PRRSv) are still poorly understood. The objectives of this large scale study were to evaluate associations between viral load and fetal preservation,...
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2003
Heuven, H. , Plastow, G., Peleman, J., Siggens, K., Brugmanns, B., Bagga, M.
AFLP® was utilized successfully as a tool to generate a large number (more than 100) of DNA markers in a total of 2435 individuals from the EC Pig Biodiversity project. This information was used for an initial genetic distance analysis with the results tending to group the lines and breeds as...
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2003
Mitsuhashi, T., Andersson, L. , Carrion, D., Haley, C., Archibald, A., Evans, G., Plastow, G., Day, A.
We describe the characterisation of the two main coat colour determining loci (MC1R and KIT) for pigs and demonstrate how this information can be utilized for breed identification. These approaches can be useful components of quality assurance and traceability schemes which are increasingly...
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Single nucleotide polymorphisms for feed efficiency and performance in crossbred beef cattle
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Squires, J. J., Moore, S., Stothard, P., Swanson, K. C., Miller, S. P., Abo-Ismail, M. K., Vander Voort, G., Liao, X., Plastow, G., Mandell, I. B.
Background This study was conducted to: (1) identify new SNPs for residual feed intake (RFI) and performance traits within candidate genes identified in a genome wide association study (GWAS); (2) estimate the proportion of variation in RFI explained by the detected SNPs; (3) estimate the...
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2014
Plastow, G., Stothard, P., Moore, S., Bao, H., Meng, Y., Liao, X.
Gene duplication is a widespread phenomenon in genome evolution, and it has been proposed to serve as an engine of evolutionary innovation. In the present study, we performed the first comprehensive analysis of duplicate genes in the bovine genome. A total of 3131 putative duplicated gene pairs...
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Quantitative trait loci affecting Rous Sarcoma Virus induced tumor regression trait in F2 intercross chickens
Download2009
Uemoto, Y., Mitsuhashi, T., Saburi, J., Miyata, T., Suzuki, K., Odawara, S., Yamashita, H., Yamamoto, R., Sato, S-I., Plastow, G., Kobayashi, E., Irina, C., Ohtake, T.
We performed a genome-wide linkage and quantitative trait locus (QTL) analysis to confirm the existence of QTL affecting Rous Sarcoma Virus (RSV) induced tumor regression, and to estimate their effects on phenotypic variance in an F2 resource population. The F2 population comprised 158 chickens...
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2011
Wang, Z., MacNeil, J. D., Stewart-Smith, J., Tang, G., Basarab, J. A., Moore, S. S., Plastow, G.
Crossbreeding is an effective method for improving the efficiency of production in commercial cow-calf operations. It exploits available heterosis (hybrid vigour) and complementarity between different breeds or populations (lines). Before adopting a crossbreeding system, commercial cattle...
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2012
Plastow, G., Lu, D., Miller, S., Moore, S., Vander Voort, G., Wang Z., Sargolzaei, M., Li, C., Kelly, M.
Linkage disequilibrium (LD) and the persistence of its phase across populations are important for genomic selection as well as fine scale mapping of quantitative trait loci (QTL). However, knowledge of LD in beef cattle, as well as the persistence of LD phase between crossbreds (C) and purebreds,...
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2013
Voort, G. V., Sargolzaei, M., Wang, Z., Moore, S., Mandell, I., Lu, D., Kelly, M., Plastow, G., Miller, S.
Background Genetic improvement of beef quality will benefit both producers and consumers, and can be achieved by selecting animals that carry desired quantitative trait nucleotides (QTN), which result from intensive searches using genetic markers. This paper presents a genome-wide association...
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Genetic and Phenotypic Correlations between Performance Traits with Meat Quality and Carcass Characteristics in Commercial Crossbred Pigs
Download2014
Wang, Z., Kemp, R., van Haandel, B., Charagu, P., Zhang, C., Bruce, H., Miar, Y., McKay, R., Huisman, A., Plastow, G., Manafiazar, G., Moore, S.
Genetic correlations between performance traits with meat quality and carcass traits were estimated on 6,408 commercial crossbred pigs with performance traits recorded in production systems with 2,100 of them having meat quality and carcass measurements. Significant fixed effects (company, sex...