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Fall 2016
. Random forest analysis, stratified by sex, tested the predictive importance of 22 risk factors derived from five documented AD risk domains: (a) demographic (e.g., education), (b) functional biomarker (e.g., pulse pressure), (c) health (e.g., diabetes), (d) mobility (e.g., walking time), and (e
genetic risk score [GRS]) is predicted by factors that are sex-specific and genetically robust. Using a longitudinal sample of cognitively normal adults (n = 642, aged 53-95) we defined memory resilience as possessing specified genetic risk while sustaining high episodic memory (EM) function over time
) lifestyle (e.g., everyday physical activity). For both sexes, younger age, higher education, stronger grip, and everyday novel cognitive activity predicted memory resilience. For females, demographic, functional, health, mobility, and lifestyle factors predicted resilience. For males, fewer depressive