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- 1Alzaben, Abeer Salman
- 1Ethier, Caroline D
- 1John Niruban, Selvanayagam
- 1MacDonald, Krista M
- 1Munasinghe, Dona, LL.
- 1Reich, Krista, M
Epidemiological studies correlate vitamin D deficiency with asthma severity. Calcitriol modulates receptor and cytokine expression from various leukocytes in an anti-inflammatory manner. Despite eosinophil activity during mucosal inflammation, knowledge on the direct effect of calcitriol on this...
The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel DiseaseDownload
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...
The prevalence and determinants of adequate vitamin D intake and supplementation among Canadian childrenDownload
Most Canadian children are not meeting the dietary recommendations for vitamin D and have not enough sun exposure to synthesize vitamin D in their skin. Vitamin D supplementation therefore seems a necessity. However, no study has examined whether vitamin D from diet and supplements combined is...
Inconsistent results have been reported in studies investigating the relationship between serum vitamin D levels and respiratory outcomes. In this thesis, data from the Canadian Health Measures Survey were used to examine the relationship between serum 25-hydroxy vitamin D [25(OH)D] levels and...
Calcium and Vitamin D Intake During Pregnancy and Postpartum in the Alberta Pregnancy Outcomes and Nutrition (APrON) StudyDownload
Calcium and vitamin D are important in maintaining a healthy pregnancy. Low intake/status has been associated with preeclampsia, preterm delivery, lower birth weight, poor fetal skeletal growth, reduced bone mass, and excessive maternal bone loss. Rarely have these nutrients been examined...
Vitamin D Supplementation and Bone Health in Adults with Diabetic Nephropathy: Preliminary Findings from a Randomized Controlled TrialDownload
Vitamin D (vitD) is a nutrient of concern in Canada particularly for those with diabetes and chronic kidney disease (CKD). Participants (18-80y) with diabetes and CKD were randomized to receive either 50mcg/day (n=33) or 1,000mcg/month (n=30) vitD3 for 6-months. Variables studied included:...
Consumer acceptance of meat depends on its colour and there is a negative bias in North America for broiler dark meat. Freezing and cooking leads to changes in meat characteristics and colour of broiler chicken thighs. The first experiment focused on the effect of freezing and cooking on broiler...
The study aim was to compare the impact of corticosteroid-free and corticosteroid-containing immunosuppressive regimes on parameters of bone health and growth in children post-liver transplant (LTX). One-hundred fifteen charts were screened, thirty-nine charts meeting study inclusion were...
Vitamin D insufficiency is highly prevalent in children (up to 40%), particularly in northern climates such as Alberta, due to reduced sunlight exposure and low intake. Although suboptimal vitamin D status and metabolic dysregulation are commonly observed in obesity, little is known about the...