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Fall 2019
Axial patterning of the developing vertebrate eye is crucial for proper axon pathfinding, as well as critically important morphogenetic events such as closure of the ocular fissure. Perturbations in eye morphogenesis can lead to ocular coloboma (failed ocular fissure closure) and microphthalmia...
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Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection
Download2020-01-01
Van Goor, Angelica, Pasternak, Alex, Walker, Kristen, Hong, Linjun, Malgarin, Carolina, MacPhee, Daniel J., Harding, John C. S., Lunney, Joan K.
Background:A pregnant gilt infected with porcine reproductive and respiratory syndrome virus (PRRSV) can transmit the virus to her fetuses across the maternal-fetal-interface resulting in varying disease outcomes. However,the mechanisms leading to variation in fetal outcome in response to PRRSV...
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Formation of taste-active amino acids, amino acid derivatives and peptides in food fermentations – A review
Download2016-11-01
Zhao, Cindy J., Schieber, Andreas, Gänzle, Michael G.
Fermented foods are valued for their rich and complex odour and taste. The metabolic activity of food-fermenting microorganisms determines food quality and generates odour and taste compounds. This communication reviews the formation of taste-active amino acids, amino acid derivatives and...
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Putting the microbiota to work: Epigenetic effects of early life antibiotic treatment are associated with immune-related pathways and reduced epithelial necrosis following Salmonella Typhimurium challenge in vitro
Download2020-04-01
Costa, Matheus O., Fouhse, Janelle, Silva, Ana Paula P., Wiling, Benjamin, Harding, John C. S.
Salmonella enterica serovar Typhimurium is an animal welfare and public health concern due to its ability to parasite livestock and potentially contaminate pork products. To reduce Salmonella shedding and the risk of pork contamination, antibiotic therapy is used and can contribute to...
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Type 2 porcine reproductive and respiratory syndrome virus infection increases apoptosis at the maternal-fetal interface in late gestation pregnant gilts
Download2017-03-01
Novakovic, Predrag, Harding, John C. S., Al-Dissi, Ahmad N., Detmer, Susan E.
The pathogenesis of fetal death associated with porcine reproductive and respiratory syndrome (PRRS) is hypothesized to be a consequence of PRRS virus-induced apoptosis at the maternal-fetal interface (MFI). The objectives of this study were to evaluate distribution and degree of apoptosis in the...
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2011-03-01
Birds can be used as indicators to monitor success of programs encouraging prairie landowners to increase biodiversity. Using a case study from Alberta, Canada, this paper compares bird diversity measures at the farm scale and examines their consistency across different habitat types to test for...
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Fall 2018
Background: Cancer-associated venous thromboembolism (VTE) is associated with significant morbidity and mortality. Cancer patients are at higher risk of VTE recurrence despite anticoagulation and bleeding complications while on anticoagulation. There are some risk factors of bleeding specific...
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Manga, Murder and Mystery: Investigating the Revival of the Boy Detective in Japan’s Lost Decade
DownloadFall 2019
The past two decades have seen a sustained growth in the number of Japanese mystery and detective comics (manga) publications that feature boys (and girls) as crime fighting agents. While the earliest incarnation of the boy detective character type can be traced to the works of Edogawa Rampo...
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Analyzing Network Connectivity by Cyclist Comfort: An Empirical Reappraisal of the Four Types of Cyclists Typology and Level of Traffic Stress Framework
DownloadFall 2019
North America is seeing a resurgence of interest in cycling both for recreation and as a transportation mode. Cycling is touted as a means to reduce traffic congestion and its GHG emissions and pollution, increase livability, and provide a remedy to inactivity and its related health problems....
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Spring 2019
Over the last few decades the incidence of obesity has increased remarkably in Canada and in the rest of the world, with the highest increases occurring in the excessive weight categories class II (BMI 35– 39.9) and class III (BMI ≥ 40). By 2019, it is anticipated that over 20% of the Canadian...