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Spring 2023
The rotating B0 linac-MR is a new type of radiotherapy treatment machine that combines radiation delivery from a linear accelerator (linac) with a magnetic resonance imaging (MRI) system for real-time tumour tracking. This kind of combined technology aims to achieve tighter margins in cancer...
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Spring 2023
There has been a renewed interest in commonsense as a stepping stone toward achieving human-level intelligence. By digesting enormous amounts of data in different forms, such as visual, lingual, and sensory, humans are able to create a world model for themselves. It is hypothesized that this...
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Spring 2023
The deployment of computation-intensive applications, such as digital signal processing (DSP) and machine-learning (ML), on resource-constrained applications is spurring research that aims to increase the power efficiency of the arithmetic circuits that perform a huge amount of...
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Novel Isotope Labeling Strategies for NMR-Based Structure Determination of High Molecular Weight Proteins
DownloadSpring 2023
Solution NMR studies of high molecular weight proteins suffer from inadequate side-chain information and rapid signal decay. Selective 1H, 13CH3-methyl labelling of perdeuterated proteins has been the standard approach addressing these limitations but suffers from a lack of information about the...
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Spring 2023
AlbertaSat is a group of researchers and students at the University of Alberta who are developing low-cost satellites with open-source software that follow the CubeSat form factor. It is one of the projects funded by the Canadian CubeSat Project, whose goal is to provide a hands-on satellite...
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Spring 2023
Five-year overall survival for gastric cancer in Canada is only 25%. Standard of care treatment using neoadjuvant chemotherapy and surgery achieves partial or complete treatment response in only 40% of patients. Additional strategies and methods to discover novel therapies and optimize existing...
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Spring 2023
Construction labour productivity (CLP) is a key performance indicator for determining the success of construction undertakings, and notably affects the profitability of construction companies. To this effect, the construction industry and researchers have pursued better ways of addressing the CLP...
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The lingering impact of sport-related knee injuries on health-related quality of life in active youth
DownloadSpring 2023
Background: It is assumed that youth who experience a knee injury while playing sports have an initial decline in health that resolves with time, leaving no lasting impact. Health-related quality of life (HRQoL) encompasses the physical, psychological, and social domains of health. It can...
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Development of novel compounds for the molecular imaging of hypoxia: 18F-labeled nitroimidazoles and hypoxia inducible factor 1 alpha (HIF-1a)-targeting compounds
DownloadSpring 2023
Imaging of hypoxia has been previously achieved using positron emission tomography (PET) with radiotracers such as [18F]fluoroazomycin arabinoside ([18F]FAZA) [1] or [18F]fluoromisonidazole ([18F]FMISO) [2]. These typical nitroimidazole containing compounds are reductively trapped in hypoxic...
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Spring 2023
The nucleus is a hallmark organelle of eukaryotes. It separates the genetic material from the rest of the cytoplasm using a selectively permeable double phospholipid bilayer called the nuclear envelope (NE). The NE contains numerous pores with embedded macromolecular structures called nuclear...