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- 36Field, Catherine J.
- 29Stothard, Paul
- 20Chan, Catherine B.
- 19Proctor, Spencer D.
- 18Weselake, Randall J.
- 17Guan, Leluo
A randomized, controlled trial of ginseng consumption on the immune response to a moderate exercise stress protocol in non-athletic womenDownload
Background: Ginseng is a popular herbal remedy that has been proposed to increase resistance to stress and enhance immune function. Regular moderate exercise results in an acute physiological stress that affects immune function. Objective: This study was conducted to investigate the effects of...
A simple procedure to secure an indwelling jugular vein catheter to the neck of cattle for repeated blood samplingDownload
Abstract A procedure to secure a jugular vein catheter system to the neck of cattle is described. A wide-mouthed polypropylene bottle attached to a halter strap provided a secure container for the catheter. This device allowed convenient access to the catheter for repeated sampling and,...
A systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomesDownload
Background The major metabolic complications of obesity and type 2 diabetes may be prevented and managed with dietary modification. The use of sweeteners that provide little or no calories may help to achieve this objective. Methods We did a systematic review and network meta-analysis of the...
Immigrants to a new country face many challenges when diagnosed with type 2 diabetes, a chronic disease with a complex treatment involving both medical and behavioral interventions. These challenges will depend upon the extent to which the patient has adapted to the new country’s social and...
Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimersDownload
Anti-oxidant capacity is crucial defence against environmental or endogenous oxidative stress. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that plays a key defensive role against oxidative and cytotoxic stress and cellular senescence. However, Nrf2...
Acyl-CoA-binding and self-associating properties of a recombinant 13.3 kDa N-terminal fragment of diacylglycerol acyltransferase-1 from oilseed rapeDownload
Nykiforuk, Cory L., Szarka, Steve J., Laroche, André, Mosimann, Steven C., Burton, Tracy L., Thibault, Benjamin J., Boora, Parveen S., Madhavji, Milan, Foroud, Nora A., Moloney, Maurice M., Wiehler, William B., Patterson, Nii A., Weselake, Randall J., Furukawa-Stoffer, Tara L.
Background Diacylglycerol acyltransferase (DGAT, EC 188.8.131.52) catalyzes the acyl-CoA-dependent acylation of sn-1, 2-diacylglycerol to generate triacylglycerol and CoA. The deduced amino acid sequence of cDNAs encoding DGAT1 from plants and mammals exhibit a hydrophilic N-terminal region followed...
Adaptation to high grain diets proceeds through minimal immune system stimulation and differences in extracellular matrix protein expression in a model of subacute ruminal acidosis in non-lactating dairy cowsDownload
Problem statement: Subacute Ruminal Acidosis (SARA) is a metabolic disorder affecting approximately 20% of all dairy cattle in North America. Although the presence of SARA has been described for some time, the etiology of the disorder remains uncertain. For example, many animals diagnosed with...
The recent technological innovations in the area of functional genomics, gene expression/transcriptomic profiling can provide new insights to understand the molecular basis of adipogenesis. The focus of this review is to highlight the recent advances in our understanding of the complex interplay...
The objectives of this study were to evaluate metabolic and innate immunity alterations in the blood of transition dairy cows before, during, and after diagnosis of lameness during periparturient period. Blood samples were collected from the coccygeal vain once per week before morning feeding...
Altered microRNA expression in bovine subcutaneous and visceral adipose tissues from cattle under different dietDownload
Background MicroRNAs (miRNAs) are a class of molecular regulators found to participate in numerous biological processes, including adipogenesis in mammals. This study aimed to evaluate the differences of miRNA expression between bovine subcutaneous (backfat) and visceral fat depots (perirenal...