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Skip to Search Results- 33Mass-spectrometry
- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Spring 2016
A unique borylative migration of heterocyclic enol perfluorosulfonates has been developed to access six-membered heterocyclic α-substituted allylboronates in a stereoselective and efficient manner. The synthetic utility of the allylboronate intermediates was demonstrated by a highly...
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Application of a Donor-Acceptor Strategy to Intercept Molecular Main Group Element Precursors en Route to Nanodimensional Materials
DownloadFall 2017
The work in this thesis describes the stabilization of reactive and elusive main group entities with the aid of Wittig reagents, transition metal complexes, or N-heterocyclic carbenes (NHCs) as donors. Wittig reagents were employed to stabilize various group 14 element dihydrides (EH2; E = Ge and...
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Application of Deuterium Isotope Effects on NMR Parameters as a Method of Intramolecular Hydrogen Bond Characterization in Enolic Forms of 1,3-diketones in the Solid State
DownloadFall 2022
The application of deuterium isotope effects on 13C NMR chemical shifts to study the nature of intramolecular hydrogen bonding in the enolic forms of two 1,3-diketones, tetraacetylethane (TAE) and avobenzone, in the solid state is reported. Carbon-13 NMR spectra of natural abundance TAE and...
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Application of Electrospray Ionization Mass Spectrometry to Study Protein-Ligand Interactions and Enzyme Kinetics
DownloadFall 2015
This thesis describes the development and application of electrospray ionization mass spectrometry (ESI-MS) to study the noncovalent protein-ligand interactions and also investigate the kinetic of enzymatic reactions. The rate of glycolipids cleavage by the human neuraminidase 3 (hNEU3) was...
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Application of Metallocarbene Decomposed from Diazoesters with Organic Azides and 1,2,3-Triazoles
DownloadSpring 2016
Metallocarbenes, in situ generated from catalytic decomposition of diazocarbonyl compounds, contain only 6 electrons at carbon center, therefore are highly electrophilic. Over the years, the metallocarbene intermediates have been continuously explored as a versatile tool toward C-C and C-X bond...