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Skip to Search Results- 1Ajamian, Farnam
- 1Archibald, Mandy M
- 1Aung, Yin N
- 1Bahreinian, Salma
- 1Elamy, Abdel-Halim H
- 1Ethier, Caroline D
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Fall 2009
International prevalence of ever asthma and current wheeze in adults were examined in 55 countries participating in the World Health Survey. The prevalence of ever asthma ranged from 1.1-7.9% in Asia, 2.4-7.6% in Africa, 3.4-7.9% in Middle East, 2.4-12.1% in America, 3.9-6.8% in Eastern Europe,...
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A large deletion virus reveals the presence of previously uncharacterized vaccinia virus inhibitors of NF-kB signaling
DownloadFall 2010
The classical Nuclear Factor kappa B (NF-κB) signaling pathway is an important regulator of inflammation and innate immune responses. Poxviruses, including vaccinia virus, encode multiple immune evasion proteins, including a growing number of NF-κB inhibitors. To determine if additional vaccinia...
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Fall 2010
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...
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Respiratory Syncytial Virus infection biases the immune response in favor of Th2: the role of Indoleamine 2, 3-dioxygenase
DownloadSpring 2012
Infants that develop severe bronchiolitis due to Respiratory Syncytial Virus (RSV) are at increased risk of developing asthma later in life. To begin my studies in vitro, purified RSV stock was needed. My first study established the critical steps in RSV purification to determine a procedure that...
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Fall 2012
Recent discoveries in stem cell biology have generated enthusiasm about the possibility of harnessing stem cells for organ repair and regeneration. The ability of pluri- and multipotent stem cells to differentiate along various cellular lineages has placed them at the core of research that seeks...
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Spring 2012
Asthma is a common chronic condition in Canadian adolescents. Stress is a proposed risk factor for asthma development. Allostatic load (AL) is a composite measure of chronic stress exposure, and its role in the development of asthma in adolescents was the focus of this thesis. In study 1, we...
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Fall 2013
Physician training influences the care that a patient receives. A retrospective cohort of children over 6 years of age, seen in a multi-disciplinary asthma clinic between 2009 and 2010 and followed to 2012, was completed to identify differences in pediatric asthma management by physician...
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Spring 2014
Inconsistent results have been reported in studies investigating the relationship between serum vitamin D levels and respiratory outcomes. In this thesis, data from the Canadian Health Measures Survey were used to examine the relationship between serum 25-hydroxy vitamin D [25(OH)D] levels and...