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Skip to Search Results- 16Bioinformatics
- 5Machine Learning
- 3Question Answering
- 2Artificial Intelligence
- 2Machine learning
- 2Metabolomics
- 10Graduate and Postdoctoral Studies (GPS), Faculty of
- 10Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 5Computing Science, Department of
- 5Computing Science, Department of/Technical Reports (Computing Science)
- 1The NSERC TRIA Network (TRIA-Net)
- 1The NSERC TRIA Network (TRIA-Net)/Journal Articles (TRIA-Net)
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2001
Schaeffer, Jonathan, Charter, K., Lu, Paul, Szafron, Duane, Parsons, I., Driga, A.
Technical report TR01-10. For two DNA or protein sequences of length m and n, dynamic programming alignment algorithms like Needleman-Wunsch and Smith-Waterman take O(m x n) time and use O(m x n) space, so we refer to them as full matrix (FM) algorithms. This space requirement means that large...
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2003
Greiner, Russ, Poulin, B., Lu, Paul, Anvik, J., Lu, Z., Macdonell, Cam, Wishart, David, Eisner, Roman, Szafron, Duane
Technical report TR03-09. Naive Bayes classifiers, a popular tool for predicting the labels of query instances, are typically learned from a training set. However, since many training sets contain noisy data, a classifier user may be reluctant to blindly trust a predicted label. We present a...
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2003
Greiner, Russell, Wishart, David, Eisner, Roman, Lu, Z., Lu, Paul, Macdonell, Cam, Poulin, B., Szafron, Duane, Anvik, J.
Technical report TR03-14. Identifying the destination or localization of proteins is key to understanding their function and facilitating their purification. A number of existing computational prediction methods are based on sequence analysis. However, these methods are limited in scope, accuracy...
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Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans
Download2003-05-13
Wen, Xiao-Yan, Hegele, Robert A., Wang, Jian, Wang, Ding Yan, Cheung, Joseph, Wilson, Michael, Yahyapour, Maryam, Bai, Yahong, Zhuang, Lihua, Skaug, Jennifer, Young, T. Kue, Connelly, Philip W., Koop, Ben F., Tsui, Lap-Chee, Stewart, A. Keith
"Triglyceride (TG) metabolism is crucial for whole body and local energy homeostasis and accumulating evidence suggests an independent association between plasma TG concentration and increased atherosclerosis risk. We previously generated a mouse insertional mutation lpd (lipid defect) whose...
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Fall 2009
Answer typing is an important aspect of the question answering process. Most commonly addressed with the use of a fixed set of possible answer classes via question classification, answer typing influences which answers will ultimately be selected as correct. Answer typing introduces the concept...
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2011
Goebel, Randy, Wang, Lusheng, Lin, Guohui, Li, Zhong
Technical report TR11-02. Given two genomic maps G1 and G2 each represented as a sequence of n gene markers, the maximal strip recovery (MSR) problem is to retain the maximum number of markers in both G1 and G2 such that the resultant subsequences, denoted as G1* and G2*, can be partitioned into...
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Fall 2011
Metabolomics aims to study all small-molecule compounds (i.e. metabolites) in cells, tissues, or biofluids. These compounds provide a functional readout of the physiological, developmental, and pathological state of a biological system. The field of metabolomics has expanded rapidly over the last...
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Estimating the Overlap of Top Instances in Lists Ranked by Correlation to Label
Spring 2012
Recent advances in high-throughput technologies, such as genome-wide SNP analysis and microar- ray gene expression profiling, have led to a multitude of ranked lists, where the features (SNPs, genes) are sorted based on their individual correlation with a phenotype. Multiple reviews have shown...
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2013
Abou-Moustafa, Karim T., Kozyrskyj, Anita, Guttman, David, Scott, James, Yasui, Yutaka
Entropy measures of probability distributions are widely used measures in ecology, biology, genetics, and in other fields, to quantify species diversity of a community. Unfortunately, entropy–based diversity indices, or diversity indices for short, suffer from three problems. First, when...