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Skip to Search Results- 1Abbasi Dezfouli, Meysam
- 1Akin, Oguz
- 1Alberti, Devin
- 1Amin, Muhammad Ruhul
- 1Bandara, Nandika P.
- 1Bayati, Fatemeh
- 13Department of Chemical and Materials Engineering
- 10Department of Mechanical Engineering
- 4Department of Chemistry
- 3Department of Civil and Environmental Engineering
- 2Department of Biomedical Engineering
- 2Department of Electrical and Computer Engineering
- 2Choi, Phillip (Chemical and Materials Engineering)
- 2Liu, Qi (Chemical and Materials Engineering)
- 2Liu, Yang (Civil and Environmental Engineering)
- 1Antoniuk, Tim (Industrial Design)
- 1Ayranci, Cagri (Mechanical Engineering)
- 1Backhouse, Chris (Electrical and Computer Engineering, University of Waterloo)
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Delivery of STAT3 inhibitor cucurbitacins to tumor by polymeric nano-carriers : Implications in cancer chemo- and immunotherapy
DownloadFall 2009
Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers and plays a critical role in tumor growth and cancer immune evasion. The focus of this dissertation is the delivery of STAT3 inhibitor cucurbitacins...
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Lipid Modified Polymers for Transfection of Human CRL Fibroblasts, and for siRNA Mediated MDR Reversal in Melanoma Cancer Therapy
DownloadFall 2010
Gene delivery for therapeutic purposes is quickly emerging as the best potential treatment option for inherited genetic diseases and cancer. Viral gene carriers have been the choice for this purpose due to their high efficiency, but harmful immunogenic and oncogenic host reactions have limited...
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The Influence of EPS Conditioning Films on Pseudomonas aeruginosa Adhesion to Solid Surfaces
DownloadFall 2010
Bacterial adhesion to inert surfaces in aquatic environments is highly dependent on the surface properties of the substratum, which could be altered significantly by the formation of conditioning films. The impacts of extracellular polymeric substances (EPS) and its several representative...
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Synthesis and Characterization of Phosphorylcholine-based Polymers and Nanogels via the Reversible Addition Fragmentation Chain Transfer Process
DownloadFall 2011
2-Methacryloyloxyethyl Phosphorylcholine is an interesting biocompatible monomer. An improved method for the synthesis of poly(MPC) and its copolymers using Reversible Addition-Fragmentation chain Transfer (RAFT) has been discussed in the first part of the thesis. Previous reports related to the...
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Fall 2011
High aspect ratio microelectromechanical structures have been found, in the literature, to collapse due to capillary forces of liquids. In this dissertation, mathematical models are developed to study (i) the collapse of a microstructure represented by a double cantilevered beam (DCB) with a free...
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Fall 2011
Coupling supercritical CO2 extraction with membrane separation leads to energy savings by recycling CO2 at supercritical state while separating extract components. Commercially available polyamide-based membranes are commonly used with coupled systems due to their availability and robust...
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Examination of the Regulation of Phosphorylation Events in Macrophage Adhesion and Response to Zymosan
DownloadFall 2012
Macrophages play a central role in innate immunity, most notably in tissue repair, phagocytosis of dead or infected cells, secretion of chemokine and cytokines at sites of infection, as well as the activation of other immune cells. These roles are highly dependent on their capacity to migrate...