SearchSkip to Search Results
- 1 Athorn, Rebecca
- 1AlZahal, Ousama
- 1Almeida, Luciane M.
- 1Badr, Dina EFA
- 1Basu, Urmila
- 1Blanes, Milena
- 9Graduate Studies and Research, Faculty of
- 9Graduate Studies and Research, Faculty of/Theses and Dissertations
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 1Chemistry, Department of
- 1Chemistry, Department of/Journal Articles (Chemistry)
Transcriptome and Proteome Based Survey to Identify Aluminum-Responsive Genes in Roots of Arabidopsis ThalianaDownload
Aluminum (Al)stress is a major limitation to crop productivity on acidic soils. To help understand the cellular mechanisms underlying the toxicity and resistance of plants to Al, this thesis involved a large-scale, transcriptomic and proteomic analysis of roots of Arabidopsis thaliana and reports...
Genetic Analysis of Lignification and Secondary Wall Development in Bast Fibers of Industrial Hemp (Cannabis sativa)Download
Industrial hemp (Cannabis sativa) is a highly productive crop that is well suited to cultivation in Canada. To better understand the development of bast (phloem) fiber secondary walls and to facilitate reverse genetics screening for improved germplasm, I undertook two sets of microarray...
Previous studies of the grey wolf (Canis lupus) using microsatellites have showed strong population structure despite the high mobility of individuals. I re-assessed the structure of North American grey wolves by genotyping 132 wolves at a genome-wide set of >26 000 single nucleotide...
Microarray analysis in caudal medulla of cattle orally challenged with bovine spongiform encephalopathyDownload
Bovine spongiform encephalopathy (BSE) is a fatal disorder in cattle characterized by progressive neurodegeneration of the central nervous system. We investigated the molecular mechanisms involved in neurodegeneration during prion infection through the identification of genes that are...
Recent advances in high-throughput technologies, such as genome-wide SNP analysis and microar- ray gene expression profiling, have led to a multitude of ranked lists, where the features (SNPs, genes) are sorted based on their individual correlation with a phenotype. Multiple reviews have shown...
In this dissertation, I discuss several important problems in the area of bio-relation discovery (BRD). Discovering bio-relations is an important problem that arises frequently in bioinformatics. It involves identifying relationships (usually pairwise) between bio-entities. These relationships...
Cancer cachexia is a multifactorial syndrome characterized by involuntary weight loss, wasting of skeletal muscle driven by reduced food intake and abnormal metabolism. Cachexia has a negative impact on quality of life, response to chemotherapy and survival. Cachexia research is undeveloped with...
Detecting, correcting, and preventing the batch effects in multi-site data, with a focus on gene expression MicroarraysDownload
Gene expression microarrays are widely used to better understand the complex biological mechanisms inside cells. One of the main obstacles of applying statistical learning algorithms to microarray data is the large gap between the number of features (p) and the number of available instances (n),...
To understand how the capacity for fat metabolism (uptake, synthesis, modification) changes in rumen epithelia immediately before and after onset of lactation in dairy cows, rumen fluid Short Chain Fatty Acid (SCFA) concentrations and mRNA expression profiles of rumen epithelia was determined in...
Light switchable optical materials from azobenzene crosslinked poly(N-isopropylacrylamide)-based microgelsDownload
4,40 -Di(acrylamido)-azobenzene was used as a crosslinker in poly(Nisopropylacrylamide)-based microgels. The microgels were subsequently used to fabricate microgel-based optical materials (etalons), which exhibited optical properties that were switchable upon exposure to UV irradiation. We also...