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- 2Al Sayah, Fatima
- 1Adame Perez, Stephany
- 1Al-Adra, David P.
- 1Albalawi, Zaina H
- 1Anderson, Sarah J
- 1Asaad, Ghada A
Living with diabetes is challenging. Achieving optimal blood sugar balance involves major lifestyle choices and changes that can be difficult to sustain over time. When a woman with diabetes immigrates to a new country with very different social and cultural customs, religion, values, norms, and...
Assessment of food accessibility, availability and adherence to dietary recommendations among diabetic older adults living in subsidized retirement homesDownload
The availability and accessibility of healthy foods for type 2 diabetes patients may limit their food choices and adherence to dietary recommendations. The accessibility and availability of food for low-income, diabetic, older adults was evaluated. Information was gathered regarding self-care...
Best practices: does it mean the same thing in the Aboriginal community as it does in the health authorities when it comes to diabetes care?Download
Best Practices: Does it mean the same thing in the Aboriginal community as it does in the Health Authorities when it comes to diabetes care?
Characterization of Human Pancreatic Beta-cell Progenitors as a Means to Alleviate the Shortage of Donor Tissue for Islet TransplantationDownload
The current shortage of islet tissue from cadaveric human donors is not sustainable and will preclude islet transplantation from becoming a widespread therapeutic treatment for those with type 1 diabetes. A potential alternative source of tissue may be through isolating, expanding, and...
Contributions of Bim and Nur77 to multiple mechanisms of T cell tolerance following high affinity antigen encounterDownload
Prevention of autoimmune disease requires the elimination or inactivation of T cells that are highly reactive to self-peptides. During T cell development in the thymus, self-reactive thymocytes undergo negative selection upon receiving a high affinity T cell receptor (TCR) signal following...
Establishing mixed hematopoietic chimerism is a promising approach to develop donor-specific tolerance to transplanted organs. Establishing tolerance may eliminate the need for long-term immunosuppressive therapy, prevent chronic rejection and in the case of Type 1 Diabetes (T1DM), reverse...
Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with DiabetesDownload
While guidelines for seasonal influenza vaccinations single out working age (< 65) adults with diabetes, vaccination rates in this group remain below national targets. Historically, there has been limited evidence to support these guidelines. This dissertation comprises four studies investigating...
Drug Exposure Definition and Healthy User Bias Impacts on the Evaluation of Oral Anti Hyperglycemic TherapiesDownload
Accurate estimation of medication use is an essential component of any pharmacoepidemiological research as exposure misclassification will threaten study validity and lead to spurious associations. Many pharmacoepidemiological studies use simple definitions, such as the categorical “any versus no...
Islet transplantation is promising treatment for certain patients with type 1 diabetes who experience recurrent episodes of hypoglycemia with unawareness. One opportunity to improve on islet transplant outcomes and potentially broaden the recipient population, is to reduce the early post...
Feeding high oleic acid Canola oil or olive oil alters inflammation, insulin resistance and lipid metabolism in a rodent model of diet induced obesityDownload
To determine the efficacy of feeding monounsaturated fatty acids (MUFA) via a high MUFA Canola oil on T2D risk factors diet induced obese rats were fed either a low fat diet (LF), a high fat low MUFA diet (HF), a high fat high MUFA olive oil diet (OO), or a high fat high MUFA Canola oil diet...