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Skip to Search Results- 1Asomaning, Justice
- 1Buijs, David, M
- 1Cheng Baron, June
- 1Duncan, A. M. Nancy.
- 1Fillmore, Natasha
- 1Halpin, Anne M
- 5Department of Agricultural, Food, and Nutritional Science
- 3Department of Pharmacology
- 3Faculty of Nursing
- 2Department of Medicine
- 2Department of Oncology
- 2Department of Physiology
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Austin, Wendy (Faculty of Nursing)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Davidge, Sandra T. (Physiology/Obstetrics and Gynecology)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
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A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
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Fall 2009
There are different opinions on who the appropriate decision makers are for extremely premature infants. Some argue the responsibility should fall to the parents, and others argue the neonatal experts should be responsible for decision making. This study explored parental perceptions of their...
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Design and synthesis of renewable lipid-based nanocarriers with thermosensitivity for targeted drug delivery applications
DownloadSpring 2024
Numerous drug molecules currently available on the market suffer from short half-life, in vivo instability, poor bioavailability, rapid degradation and inappropriate distribution. While nanocarriers have emerged as a promising solution to address these issues, the primary objective and challenge...
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Fall 2016
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....
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Spring 2016
Heart failure is associated with major changes in cardiac energy metabolism that decrease cardiac efficiency, which can reduce cardiac function. In severe heart failure there is a shift back toward a fetal heart metabolism, with a decrease in mitochondrial oxidative metabolism and increase in...
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Growth of oleaginous yeasts on mixed C5 and C6 sugar streams to generate lipid feedstocks for renewable hydrocarbon production
DownloadSpring 2022
Microbial lipids are a promising feedstock to produce renewable fuels. Lignocellulosic feedstocks can provide multiple carbon sources for microbial growth, such as hexoses (C6) and pentoses (C5). Oleaginous yeasts can convert C5 and C6 sugars to microbial lipids that can be further processed into...
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Fall 2022
Background: Although pediatric heart transplantation is a life-saving and effective therapy for children with cardiac disease, barriers remain due to a lack of available organs as well as transplant failure due to rejection. This dissertation aimed to increase knowledge related to immune risk...