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- 2Cochrane Acute Respiratory Infections Group
- 1Ambulatory Care
- 2Bialy, Liza M.
- 2Fernandes, Ricardo M.
- 2Hartling, Lisa
- 2Johnson, David W.
- 2Klassen, Terry P.
- 2Patel, Hema
Background: Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. Objectives: To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. Search methods: We searched CENTRAL (2010, Issue 3) which contains the...
From the trenches: a cross-sectional study applying the GRADE tool in systematic reviews of healthcare interventions.Download
Background GRADE was developed to address shortcomings of tools to rate the quality of a body of evidence. While much has been published about GRADE, there are few empirical and systematic evaluations. Objective To assess GRADE for systematic reviews (SRs) in terms of inter-rater agreement and...
BACKGROUND: Previous systematic reviews have not shown clear benefit of glucocorticoids for acute viral bronchiolitis, but their use remains considerable. Recent large trials add substantially to current evidence and suggest novel glucocorticoid-including treatment approaches. OBJECTIVES: To...