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Skip to Search Results- 2Berry, Tanya R
- 2Veldhoen, Richard
- 1Abbasi Dezfouli, Meysam
- 1Aburahess, Salah
- 1Akuamoah Boateng, Maxwell
- 1Alberta Centre for Active Living
- 37Graduate and Postdoctoral Studies (GPS), Faculty of
- 37Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 3Kinesiology, Sport, and Recreation, Faculty of
- 2Kinesiology, Sport, and Recreation, Faculty of/Research Data and Materials (Kinesiology, Sport, and Recreation)
- 1St. Stephen's College
- 1St. Stephen's College/Department of Psychotherapy and Spirituality (St. Stephen's College)
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Spring 2002
Alberta Centre for Active Living
Four articles on topics such as the effect of physical activity on fibromyalgia, breast cancer, and osteoporosis. One article also focuses on older Aboriginal women.
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Investigation of the BRCT repeats in human hereditary breast cancer and DNA damage response
DownloadFall 2009
The C-terminal region of breast cancer susceptibility gene 1 (BRCA1) contains a pair of tandem BRCT repeats that are critical for the tumour suppressor function of BRCA1. BRCT repeats are present in a large of number of proteins that are implicated in the cellular response to DNA damage. A subset...
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Lipid Modified Polymers for Transfection of Human CRL Fibroblasts, and for siRNA Mediated MDR Reversal in Melanoma Cancer Therapy
DownloadFall 2010
Gene delivery for therapeutic purposes is quickly emerging as the best potential treatment option for inherited genetic diseases and cancer. Viral gene carriers have been the choice for this purpose due to their high efficiency, but harmful immunogenic and oncogenic host reactions have limited...
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Association mapping of genes using whole genome polymorphism arrays: Identification of markers of breast cancer susceptibility in Alberta women
DownloadFall 2010
Chakravarthy Sridharan, Malinee
Breast cancer is a heterogeneous, polygenic disease and is influenced by genetic, environmental and life-style factors. Many single nucleotide polymorphisms (SNPs) associated with breast cancer risk have been identified in genome-wide association studies (GWASs) by several research groups for...
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Fall 2010
Breast cancer is the most common cancer and the leading cause of cancer-related death among Canadian women. Despite improvements in treatment and early detection, there is still a need to develop novel therapies for breast cancer management. Aberrant Notch signaling is tumorigenic and is...
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Fall 2011
Taxanes are used for the treatment of breast, ovarian, and lung cancer. Unfortunately, taxane based therapy—the current treatment for metastatic breast cancer—has substantial shortcomings including myelosupression, neurotoxicity, and frequently acquired resistance. Our present understanding of...
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Fall 2011
Taxanes are used for the treatment of breast, ovarian, and lung cancer. Unfortunately, taxane based therapy—the current treatment for metastatic breast cancer—has substantial shortcomings including myelosupression, neurotoxicity, and frequently acquired resistance. Our present understanding of...
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Spring 2012
In Pulmonary Arterial Hypertension (PAH), pro-constrictive, pro-proliferative and anti-apoptotic diatheses converge to produce contraction and excessive proliferation of pulmonary artery smooth muscle cells (PASMC), a hallmark of PAH-vascular remodeling. The increased afterload causes right...
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Fall 2012
Taxane chemotherapy is widely used in the treatment of breast cancer. Despite its widespread clinical use, the molecular mechanisms of paclitaxel induced apoptosis remain unclear. Our laboratory has identified an important role for the BH3-only protein, BAD, in the paclitaxel induced cell death...