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Skip to Search Results- 1Bishop, Justin G
- 1Collins, Catherine
- 1Collins, Catherine Elizabeth Victoria
- 1Fast, David
- 1Hosseini, Seyedeh Nargess
- 1Jensen, Lionel D
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The mechanism of action of cidofovir and (S)-9-(3-hydroxy-2-phosphonomethoxypropyl)adenine against viral polymerases
DownloadFall 2009
The nucleoside phosphonates cidofovir (CDV) and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine [(S)-HPMPA] are analogs of dCMP and dAMP, respectively. Collectively these drugs are effective inhibitors of a wide range of DNA viruses, RNA viruses, and retroviruses. Because they are nucleotide...
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Fall 2010
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...
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Removal of model waste-water bacteria by magnetite in water and waste-water treatment processes
DownloadFall 2012
Conventional disinfection processes used for water and waste-water treatment such as chlorination, and ozonation produce disinfection by products which are carcinogenic. The use of magnetite as an alternative method of removing pathogenic microorganisms from the water streams was proposed as it...
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Fall 2012
Bacterial conjugation is the process of plasmid DNA transfer from a donor cell to a recipient cell. This process is mediated in F-like plasmids by proteins expressed by the tra operon. The relaxosome forms at oriT (origin of transfer), where the nicking and unwinding of a single-stranded copy of...
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The ecology of boreal forest floor microbial communities in relation to environmental factors
DownloadFall 2012
Soil microbial communities in boreal forests are structured by complex interactions among many factors operating simultaneously on large and small spatial scales. Of particular note in the boreal mixedwood, the microbial communities under trembling aspen and white spruce forest floors are...
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Fall 2012
Provided that infectious prions (PrPTSE) are inactivated, composting of specified risk material (SRM) may be a viable alternative to rendering and land filling. The overall objective of this research was to utilize laboratory-scale composters to assess the degradation of SRM and PrPTSE during...
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Interactions Between Host Trees, Bacteria, and Fungi: Impacts on Mountain Pine Beetle (Dendroctonus ponderosae) Reproduction
DownloadFall 2012
Warming winter trends due to climate change have allowed for a range expansion of the mountain pine beetle, and the beetle now threatens Canada’s economically and ecologically important jack pine forests. The beetle’s success in jack pine trees will depend upon successful colonization of the...
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Fall 2013
The inactivation fluence of a target wastewater plant in Alberta, Canada was determined in the laboratory and was found to be close to that reported by the target wastewater plant. The effect of inactivation fluence, effective reactivation fluence, temperature, and river water on the percent...
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Fall 2013
Collins, Catherine Elizabeth Victoria
Surface mining for bitumen extraction results in production of tailings that are deposited into large ponds. Tailings in the ponds support diverse microbial communities capable of metabolizing organic compounds and producing biogenic gases (methane, CH4 and carbon dioxide, CO2). Because of low...
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Insights into temperature adaptation in the Thermotogae gained through transcriptomics and comparative genomics
DownloadFall 2014
Thermophilic microbes are extremophiles that live at high temperatures. In order to survive and maintain function of their biological molecules, they have a suite of characteristics not found in organisms that grow at moderate temperatures (mesophiles) that range from the cellular to the protein...