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Skip to Search Results- 6Kitova, Elena N.
- 6Klassen, John S.
- 4Li, Jun
- 2Bagal, Dhanashri
- 2Boraston, Alisdair B.
- 2Campuzano, Iain D. G.
- 9Graduate and Postdoctoral Studies (GPS), Faculty of
- 9Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 8Chemistry, Department of
- 8Chemistry, Department of/Journal Articles (Chemistry)
- 1St. Stephen's College
- 1St. Stephen's College/Department of Psychotherapy and Spirituality (St. Stephen's College)
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Quantifying labile protein-ligand interactions using electrospray ionization mass spectrometry
Download2010
El-Hawiet, Amr, Klassen, John S., Kitova, Elena N., Liu, Lan
A new electrospray ionization mass spectrometry (ES-MS) approach for quantifying protein—ligand complexes that are prone to in-source (gas-phase) dissociation is described. The method, referred to here as the reference ligand ES-MS method, is based on the direct ES-MS assay and competitive ligand...
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Quantifying labile protein-ligand interactions using electrospray ionization mass spectrometry
Download2010
El-Hawiet, Amr, Liu, Lan, Klassen, John S., Kitova, Elena N.
A new electrospray ionization mass spectrometry (ES-MS) approach for quantifying protein—ligand complexes that are prone to in-source (gas-phase) dissociation is described. The method, referred to here as the reference ligand ES-MS method, is based on the direct ES-MS assay and competitive ligand...
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Spring 2012
This thesis is concerned with understanding the shame that often accompanies acne and acne scarring, as an instance of shame that accompanies bodily abnormality or disability, with the aim of exploring strategies of resistance. (1) I explore the explanandum by appealing to the language used by...
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The Influence of Specific Ions and System Architecture on the Recognition and Reactivity of Two Charged Materials: DNA-Modified Gold Nanoparticle Aggregates and Planar Silica
DownloadFall 2014
DNA functionalized gold nanoparticles (GNP–DNA) offer simple colorimetric nucleic acid sensing with high selectivity and sensitivity. Consequently, they are promising in genetic profiling, disease diagnostics, and forensic applications. In the presence of a target nucleic acid, GNP–DNA forms...
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Self-Conscious Emotion and Existential Concerns: An Examination of the Effect of Shame on Death-Related Thoughts
DownloadSpring 2014
Shame is an emotionally painful experience that is commonly encountered in psychotherapy, typically involving a sense of exposure, negative self-judgment, and a strong desire to withdraw or hide. Such features reflect a perceived loss of status and safety in the world, issues that are of central...
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Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation
2014
Macauley, M. S., Cheng, T. Y., Moody, D. B., Paulson, J. C. , Kawasaki, N., Van Rhijn, I., Rillahan, C. D.
Lipids from mycobacteria can be presented to human T cells by group 1 CD1 Ag-presenting molecules (CD1a, CD1b, and CD1c). Group 1 CD1-restricted T cells are activated by lipid Ags presented by myeloid dendritic cells (DCs), after which they generate antibacterial effector functions, including...
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Protein-glycolipid interactions studied in vitro using ESI-MS and nanodiscs: Insights into the mechanisms and energetics of binding
Download2015
Nikjah, Sanaz, Boraston, Alisdair B., Lin, Hong, Kitova, Elena N., Li, Jun, Pluvinage, Benjamin, Han, Ling Han, Klassen, John S.
Electrospray ionization-mass spectrometry (ESI-MS) analysis combined with the use of nanodiscs (NDs) to solubilize glycolipids (GLs) has recently emerged as a promising analytical method for detecting protein–GL interactions in vitro and, when applied to libraries of GLs, ranking their...
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Fall 2015
In this dissertation, I undertake a critical analysis of the conception of community at work in what is termed “identity-based politics.” Working with Hannah Arendt’s implicit argument about place and visibility, I develop a theory of recognition in order to rethink the nature of community. The...