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- 31Graduate Studies and Research, Faculty of
- 31Graduate Studies and Research, Faculty of/Theses and Dissertations
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- 6Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy)
- 3Chemistry, Department of
- 3Chemistry, Department of/Journal Articles (Chemistry)
Third-generation optoelectronics, which utilize nanoscale materials, have received a considerable amount of attention in the chemical sciences and are poised to make a large impact in both fundamental research and real-world application. In order to make a contribution to the field, this thesis...
Germanium nanomaterials have many potential applications based on their size-tunable optical and electronic properties, for example in photodetectors, photovoltaics and non-volatile memory. In this work, the synthesis of Ge nanoparticles by two different methods based on tailorability through the...
Dendritic cells (DCs) play a central role in shaping antigen-specific immune response. Antibody-mediated antigen targeting to DC-specific surface receptors is a promising approach to enhance vaccine efficacy. The objective of this thesis was to develop DC-targeted nanoparticulate formulations for...
The use of nanoparticles as nutrient delivery vehicles enables the enhancement of the oral bioavailability and health promoting benefits of bioactive compounds. Barley protein nanoparticles were developed in previous study for hydrophobic compound delivery. The objective of the present study was...
Aquatic organisms are susceptible to waterborne nanoparticles and there is only limited understanding of the mechanisms by which these emerging contaminants affect biological processes. The unique properties of nanomaterials necessitate evaluation of standard toxicity testing techniques to...
Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic SpeciesDownload
We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
Benign-by-Design: Synthesis of Engineered Silicon Nanoparticles and their Application to Oil Sands Water Contaminant RemediationDownload
Oil sands are naturally occurring mixtures of sand or clay, water, fine silts, and bitumen. The oil sands extraction process consumes large volumes of water (i.e., ca. 3 barrels of fresh water for every 1 barrel of oil). Following the extraction of bitumen from the oil sands, a tailings slurry...
There are many candidate technologies that could be applied to the treatment of oil sands process-affected water (OSPW). Advanced oxidation processes (AOPs) are particularly useful for degrading biologically toxic or non-degradable materials such as aromatics, pesticides, petroleum constituents,...
A new aerosol particle classiﬁer, the Aerodynamic Aerosol Classifier (AAC), is presented with some of its applications. The instrument uses a centrifugal force and sheath flow between two concentric rotating cylinders to produce a monodisperse aerosol classified by aerodynamic diameter. Since...
The objective of this research was to explore the feasibility of using SPI nanoparticles to improve the absorption of vitamin B12 (VB12) using in-vitro and ex-vivo models. The molecular interactions between soy proteins and VB12 were firstly studied and the results revealed that VB12 was bound to...