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- 3Majumder, Kaustav
- 3Wu, Jianping
- 2Chakrabarti, Subhadeep
- 2Davidge, Sandra T.
- 2Jahandideh, Forough
- 2Kaufman, Susan
- 7Graduate Studies and Research, Faculty of
- 7Graduate Studies and Research, Faculty of/Theses and Dissertations
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 1Nursing, Faculty of
- 1Nursing, Faculty of/Chronicity
Beneficial effects of simulated gastro-intestinal digests of fried egg and its fractions on blood pressure, plasma lipids and oxidative stress in spontaneously hypertensive ratsDownload
Background We have previously characterized several antihypertensive peptides in simulated digests of cooked eggs and showed blood pressure lowering property of fried whole egg digest. However, the long-term effects of this hydrolysate and its fractions on blood pressure are not known. Therefore,...
Effects of Egg White Derived Peptides on Metabolic Syndrome Complications: Hypertension, Inflammation, and Insulin resistanceDownload
Metabolic syndrome (MetS), a cluster of several abnormalities of hypertension, inflammation, glucose intolerance and dyslipidemia, enhances a personâs risk for cardiovascular disease and type 2 diabetes. The number of people with MetS is increasing largely worldwide. The multi-faceted nature of...
Background There is a growing interest in using functional food components as therapy for cardiovascular diseases such as hypertension. We have previously characterized a tri-peptide IRW (Ile-Arg-Trp) from egg white protein ovotransferrin; this peptide showed anti-inflammatory, anti-oxidant and...
Hemodynamic Changes in the Prefrontal Cortex during Functional Activation in Essential Hypertension Measured by Near Infrared SpectroscopyDownload
Chronic hypertension induces microvascular changes in the prefrontal cortex (PFC) which could influence oxygenation status. However, hypertension-related changes in oxygenation in the PFC and cognition, especially during functional stresses, remain poorly investigated. This project consisted of...
Angiotensin II signals cardiovascular disease through metalloproteinases including MMP-2, MMP-7 and ADAM-17/TACE. We hypothesized that these metalloproteinases regulate each other at the transcriptional level. Further, MMP-2, being a major gelatinase in cardiac and vascular tissue, could mediate...
Despite many decades of research and drug development, the diseases of the cardiovascular system remain a major health threat in the modern world. Hypertensive cardiac disease is a cardiovascular condition characterized by the co-occurrence of hypertension and pathological cardiac remodeling...
Molecular targets of antihypertensive peptides: Understanding the mechanisms of action based on the pathophysiology of hypertensionDownload
There is growing interest in using functional foods or nutraceuticals for the prevention and treatment of hypertension or high blood pressure. Although numerous preventive and therapeutic pharmacological interventions are available on the market, unfortunately, many patients still suffer from...
Pharmacist Management of Hypertension: An Examination of Clinical and Economic Outcomes and Remuneration for Expanded ServicesDownload
Background: One-third of Canadian adults with hypertension remain uncontrolled. As drug therapy experts, pharmacists can play a role in addressing this challenge, particularly when utilizing prescribing authorization in Alberta. However, the clinical effectiveness of pharmacist management of...
Introduction: Lumbar Spinal Stenosis (LSS) is a prevalent musculoskeletal condition affecting 8-11% of the United States general population. LSS is the most common reason requiring lumbar spine surgery in adults older than 65 years, with an adjusted rate of 135.5 low back surgeries per 100,000...