ERA Banner
Download Add to Cart Share
More Like This
  • http://hdl.handle.net/10402/era.26800
  • Photothermal effects and mesoporous silica encapsulation of silicon nanocrystals
  • Regli, Sarah
  • English
  • silicon nanocrystals
    photothermal
    mesoporous silica encapsulation
    drug-delivery
    photoluminescence
    multifunctional materials
  • May 31, 2012 3:16 PM
  • Thesis
  • English
  • Adobe PDF
  • 62088227 bytes
  • The present thesis describes preliminary studies required for evaluating silicon nanocrystals (Si-NCs) as photothermal (PT) therapy agents and drug delivery vehicles. Group 14 semiconductor NCs are of particular interest for these applications because of their tailorable optical response and biological inertness. Detailed studies of the PT efficiencies of different sized Si-NCs were performed. It was found the PT response exhibited by the presented Si-NCs showed a clear size dependence leading to the proposal that its origin is dominant due to the phenomenon of carrier cooling. Mesoporous silica is a promising material for drug delivery applications because of its intrinsic high surface area and tailorable pore size. A surfactant-templated approach is described within this thesis that affords effective encapsulation of Si-NCs within 30 nm mesoporous silica nanospheres, The resulting photoluminescent particles were evaluated in proof-of-concept drug release investigations.
  • Regli, Sarah (2011). MRS proceedings http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8279193&fulltextType=RA&fileId=S1946427411007846
  • Master's
  • Master of Science
  • Department of Chemistry
  • Spring 2012
  • Veinot, Jonathan G.C. (Chemistry)
  • Gibbs-Davis, Julianne (Chemistry)
    Hegmann, Frank (Physics)