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  • http://hdl.handle.net/10402/era.24937
  • Assessing White Matter Cortical Organization using Diffusion Tensor Imaging Post-Facial Reanimation Surgery
  • Phangureh, Navneet K
  • English
  • diffusion tensor imaging (DTI)
    facial reanimation surgery
    white matter
    moebius syndrome
    bell's palsy
  • Jan 5, 2012 11:10 AM
  • Thesis
  • English
  • Adobe PDF
  • 5465704 bytes
  • The purpose of this study was to determine whether diffusion tensor imaging (DTI) could detect cortical differences between people post-facial reanimation surgery compared to matched controls. Five primary white matter tracts were analyzed for fractional anisotropy (FA) and mean diffusivity (MD) and compared between 4 patients with facial reanimation surgery (ages 11 to 47 years) and their matched controls. Findings were in the predicted direction of lower FA and higher MD in regions of the brain containing corticobulbar tract (CBT) in the facial reanimation group compared to matched controls. This finding indicated that neural tracts associated with facial movements may have less white matter fibre tract integrity in this group of patients who have undergone reanimation surgery secondary to facial paralysis. The use of DTI tractography analysis may be useful in understanding underlying neural mechanisms of change following facial reanimation surgery and ultimately serve to inform surgical and rehabilitation processes.
  • Master's
  • Master of Science
  • Department of Speech Pathology and Audiology
  • Speech-Language Pathology
  • Spring 2012
  • Boliek, Dr. Carol (Speech Pathology and Audiology)
  • Cummine, Dr. Jacqueline (Speech Pathology and Audiology)
    Olson, Dr. Jaret (Surgery)
    Wilkes, Dr. Gordon (Surgery)