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Permanent link (DOI): https://doi.org/10.7939/R3KK94M5J

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Virus Induced Asthma Exacerbations: Immunologic Mechanisms and Metabolomic Biomarkers Open Access

Descriptions

Other title
Subject/Keyword
Virus
Asthma
Metabolomics
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Skappak, Christopher Dustin
Supervisor and department
Adamko, Darryl J. (pediatrics)
Examining committee member and department
Lopashuck, Gary (Pediatrics)
Jacoby, David (Medicine - Oregon State Health University)
Befus, Dean (Medicine)
Lehner, Richard (Pediatrics)
Department
Medical Sciences-Paediatrics
Specialization

Date accepted
2014-04-02T14:59:36Z
Graduation date
2014-06
Degree
Doctor of Philosophy
Degree level
Doctoral
Abstract
This thesis examines the pathophysiology of asthma, attempts to determine the cellular mechanisms behind viral-induced immune memory mediated asthma exacerbations, and investigates urinary metabolomic biomarkers of asthma and neonatal hypoxia.
Language
English
DOI
doi:10.7939/R3KK94M5J
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
Citation for previous publication
Skappak C, Regush S, Cheung PY, Adamko DJ. “Identifying hypoxia in a newborn piglet model using urinary NMR metabolomic profiling” PLOS One. 2013 May 31;8(5):e65035. doi: 10.1371/journal.pone.0065035. Print 2013.

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2014-06-15T07:01:57.770+00:00
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File format: pdf (Portable Document Format)
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File size: 4986531
Last modified: 2015:10:12 14:43:13-06:00
Filename: Skappak_Christopher_D._201406_PhD_Virus Induced Asthma Exacerbations Immunologic Mechanisms and Metabolomic Biomarkers.pdf
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Status message: File header gives version as 1.4, but catalog dictionary gives version as 1.3
File title: Thesis Skappak Combined V1.8 - submitted
File author: Christopher Skappak
Page count: 154
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