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Permanent link (DOI): https://doi.org/10.7939/R3K97W

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Nutritional mitigation strategies for antibiotic free broiler production Open Access

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Other title
Subject/Keyword
innate immunity
25 hydroxy vitamin D3
pro-inflammatory cytokine genes
ileal morphology
broiler
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Ton, Kim Ph
Supervisor and department
Zuidhof, Martin J. (Agricultural, Food, and Nutritional Science)
Examining committee member and department
Fitzsimmons, Carolyn J. (Agricultural, Food, and Nutritional Science)
Korver, Doug R. (Agricultural, Food, and Nutritional Science)
Guan, Leluo (Agricultural, Food, and Nutritional Science)
Department
Department of Agricultural, Food, and Nutritional Science
Specialization
Animal Science
Date accepted
2013-10-03T10:50:42Z
Graduation date
2013-11
Degree
Master of Science
Degree level
Master's
Abstract
Nutritional strategies to mitigate the loss of broiler performance due to the elimination of prophylactic antibiotics were investigated, consisting of two nutrient density starter diets (HIGH: 3,025 kcal/kg and 23.9% CP; LOW: 2,858 kcal/kg and 22.3% CP), 25-OH-D3 (0 or 69 µg/kg), and bacitracin methylene disalicylate (BMD®110; 0.5g/kg). All groups received the same basal diet for grower (3,150 kcal/kg, 21.7% CP) and finisher phases (3,200 kcal/kg, 20.0% CP). On d 14, subsets of broilers (n=128) were randomly selected, and either injected with Salmonella typhimurium lipopolysaccharide, or remained non-injected (n=64). The LOW diet decreased breast yield, body weight, and feed efficiency. BMD reduced mortality and interleukin-1β mRNA expression. 25-OH-D3 increased expression of LPS-induced tumor necrosis factor alpha and inducible nitric oxide synthase mRNA in the non-LPS group. A necrotic enteritis outbreak could have increased inflammatory response in the 25-OH-D3 birds, and may have led to decrease breast yield in this group.
Language
English
DOI
doi:10.7939/R3K97W
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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