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Permanent link (DOI): https://doi.org/10.7939/R3WD02

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Barley protein based microcapsules for nutraceutical delivery Open Access

Descriptions

Other title
Subject/Keyword
β-carotene
oxidative stability
fish oil
barley protein
microencapsulation
controlled release
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Wang, Ruoxi
Supervisor and department
Dr. Lingyun Chen (Agricultural, Food and Nutritional Science)
Examining committee member and department
Dr. Tian Tang (Mechanical Engineering)
Dr. Jonathan Curtis (Agricultural, Food and Nutritional Science)
Department
Department of Agricultural, Food and Nutritional Science
Specialization

Date accepted
2011-01-07T19:43:40Z
Graduation date
2011-06
Degree
Master of Science
Degree level
Master's
Abstract
Barley protein based microcapsules (1-5µm) incorporating fish oil/β-carotene were successfully prepared. Well suspended solid microcapsules, rather than emulsions, were able to form after high pressure emulsifying process. These wet-status microcapsules could be turned into dry powder by a spray drying process. The microcapsules demonstrated spherical shape and high loading capacity. Oxidative stability tests under accelerated conditions and in food formulations suggest barley proteins are effective microencapsulation materials to protect fish oil against oxidation. Microcapsule degradation and bioactive compound release behaviors were studied in the simulated gastro-intestinal tract. The data revealed that nano-encapsulations (20-30nm) were formed as a result of enzymatic degradation of microcapsule bulk matrix in the simulated gastric tract. These nano-encapsulations delivered β-carotene to a simulated human intestinal tract intact, where they were degraded by pancreatic enzymes and steadily released the β-carotene. These uniquely structured microcapsules may provide a new strategy to develop target delivery systems for nutraceuticals
Language
English
DOI
doi:10.7939/R3WD02
Rights
License granted by Ruoxi Wang (ruoxi1@ualberta.ca) on 2011-01-07T01:16:20Z (GMT): Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of the above terms. The author reserves all other publication and other rights in association with the copyright in the thesis, and except as herein provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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