ERA

Download the full-sized PDF of The changing causal foundations of cancer-related symptom clustering during the final month of palliative care: A longitudinal studyDownload the full-sized PDF

Analytics

Share

Permanent link (DOI): https://doi.org/10.7939/R3B56Z

Download

Export to: EndNote  |  Zotero  |  Mendeley

Communities

This file is in the following communities:

Nursing, Faculty of

Collections

This file is in the following collections:

Chronicity

The changing causal foundations of cancer-related symptom clustering during the final month of palliative care: A longitudinal study Open Access

Descriptions

Author or creator
Olson, K.
Hayduk, L.
Cree, M.
Cui, Y.
Quan, H.
Hanson, J.
Lawlor, P.
Strasser, F.
Additional contributors
Subject/Keyword
System
Lung cancer
Patient
Assessment scale
Fatigue
Validation
Depression
Anorexia
Pain
Anxiety
Type of item
Journal Article (Published)
Language
English
Place
Time
Description
Background: Symptoms tend to occur in what have been called symptom clusters. Early symptom cluster research was imprecise regarding the causal foundations of the coordinations between specific symptoms, and was silent on whether the relationships between symptoms remained stable over time. This study develops a causal model of the relationships between symptoms in cancer palliative care patients as they approach death, and investigates the changing associations among the symptoms and between those symptoms and well-being. Methods: Complete symptom assessment scores were obtained for 82 individuals from an existing palliative care database. The data included assessments of pain, anxiety, nausea, shortness of breath, drowsiness, loss of appetite, tiredness, depression and well-being, all collected using the Edmonton Symptom Assessment System (ESAS). Relationships between the symptoms and wellbeing were investigated using a structural equation model. Results: The model fit acceptably and explained between 26% and 83% of the variation in appetite, tiredness, depression, and well-being. Drowsiness displayed consistent effects on appetite, tiredness and well-being. In contrast, anxiety's effect on well-being shifted importantly, with a direct effect and an indirect effect through tiredness at one month, being replaced by an effect working exclusively through depression at one week. Conclusion: Some of the causal forces explaining the variations in, and relationships among, palliative care patients' symptoms changed over the final month of life. This illustrates how investigating the causal foundations of symptom correlation or clustering can provide more detailed understandings that may contribute to improved control of patient comfort, quality of life, and quality of death.
Date created
2008
DOI
doi:10.7939/R3B56Z
License information
Creative Commons Attribution 3.0 Unported
Rights

Citation for previous publication
Olson, K., Hayduk, L., Cree, M., Cui, Y., Quan, H., Hanson, J., Lawlor, P, Strasser, F. (2008). The changing causal foundations of cancer-related symptom clustering during the final month of palliative care: A longitudinal study. Medical Research Methodology, 8(36), 1-11. doi:10.1186/1471-2288-8-36.
Source
Link to related item

File Details

Date Uploaded
Date Modified
2014-04-24T22:02:55.346+00:00
Audit Status
Audits have not yet been run on this file.
Characterization
File format: pdf (Portable Document Format)
Mime type: application/pdf
File size: 480844
Last modified: 2015:10:12 11:38:42-06:00
Filename: BMCMRM_8_2008_36.pdf
Original checksum: bee47fbb5e7044732474cd49ef6cb2d9
Well formed: true
Valid: false
Status message: Invalid destination object offset=458932
Status message: Invalid destination object offset=458932
Status message: Invalid destination object offset=458932
Status message: Invalid destination object offset=458932
Status message: Invalid destination object offset=458932
File title: Abstract
File title: 1471-2288-8-36.fm
File author: abdulkadir.sufi
Page count: 11
Activity of users you follow
User Activity Date