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Permanent link (DOI): https://doi.org/10.7939/R3QM43

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Sensory Nerve Injuries: Advances in Diagnosis and Novel Therapy to Enhance Sensory Recovery in Humans Open Access

Descriptions

Other title
Subject/Keyword
stimulation
nerve
recovery
electrical
regeneration
sensory
injury
diagnosis
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Wong, Joshua
Supervisor and department
Olson, Jaret (Surgery/Plastic Surgery)
Chan, K. Ming (Physical Medicine and Rehabilitation/Neuroscience)
Examining committee member and department
Morhart, Michael (Surgery/Plastic Surgery)
Collins, David (Neuroscience/Physical Education)
Churchill, Thomas (Surgery/External Examiner)
Department
Department of Surgery
Specialization
Experimental Surgery
Date accepted
2013-08-28T15:40:13Z
Graduation date
2013-11
Degree
Master of Science
Degree level
Master's
Abstract
The unique difference between central and peripheral nervous systems is that regeneration actually occurs in the periphery. However, the functional recovery after surgical repair is highly variable and return to pre-injury state despite surgical advances is rare. When specifically looking at sensory regeneration, the functional recovery is even worse, where less than half of patients who receive operative repair have satisfactory recovery. Another problem lies in the paucity of knowledge regarding diagnosis of sensory nerve injury. This thesis reviews the current literature regarding sensory nerve regeneration, and subsequently investigates two critical voids in the literature: first, the diagnostic precision of several available sensory tests are described when looking at complete nerve transection; and second, the effect of novel post-surgical electrical stimulation on human sensory nerve recovery is reported in a randomized controlled trial.
Language
English
DOI
doi:10.7939/R3QM43
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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