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Permanent link (DOI): https://doi.org/10.7939/R3PV6B97H

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A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project Open Access

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Author or creator
Stothard, Paul
Liao, Xiaoping
Arantes, Adriano S.
De Pauw, Mary
Coros, Colin
Plastow, Graham S.
Sargolzaei, Mehdi
Crowley, John J.
Basarab, John A.
Schenkel, Flavio
Moore, Stephen
Miller, Stephen P.
Additional contributors
Subject/Keyword
Whole-Genome Sequencing
Bos taurus
Beef
Dairy
Type of item
Journal Article (Published)
Language
English
Place
Time
Description
Background The Canadian Cattle Genome Project is a large-scale international project that aims to develop genomics-based tools to enhance the efficiency and sustainability of beef and dairy production. Obtaining DNA sequence information is an important part of achieving this goal as it facilitates efforts to associate specific DNA differences with phenotypic variation. These associations can be used to guide breeding decisions and provide valuable insight into the molecular basis of traits. Findings We describe a dataset of 379 whole-genome sequences, taken primarily from key historic Bos taurus animals, along with the analyses that were performed to assess data quality. The sequenced animals represent ten populations relevant to beef or dairy production. Animal information (name, breed, population), sequence data metrics (mapping rate, depth, concordance), and sequence repository identifiers (NCBI BioProject and BioSample IDs) are provided to enable others to access and exploit this sequence information. Conclusions The large number of whole-genome sequences generated as a result of this project will contribute to ongoing work aiming to catalogue the variation that exists in cattle as well as efforts to improve traits through genotype-guided selection. Studies of gene function, population structure, and sequence evolution are also likely to benefit from the availability of this resource.
Date created
2015/10/26
DOI
doi:10.7939/R3PV6B97H
License information
Attribution 4.0 International
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Citation for previous publication
Stothard, P., Liao, X., Arantes, A.S., De Pauw, M., Coros, C., Plastow, G.S., Sargolzaei, M., Crowley, J.J., Basarab, J.A., Schenkel, F., Moore, S., Miller, S.P. (2015) A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project. GigaScience 4:49 doi: 10.1186/s13742-015-0090-5
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File format: pdf (Portable Document Format)
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File title: Abstract
File title: A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project
File author: Paul Stothard
Page count: 3
File language: EN
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