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Permanent link (DOI): https://doi.org/10.7939/R3312W

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Percutaneous vertebroplasty for osteoporotic vertebral compression fracture Open Access

Descriptions

Other title
Subject/Keyword
safety
efficacy
vertebroplasty
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Golmohammadi, Kamran
Supervisor and department
Lambert, Robert (Radiology and Diagnostic Imaging)
Examining committee member and department
Jones, Allyson (Physical Therapy)
Lambert, Robert (Radiology and Diagnostic Imaging
Filipow, Larry (Radiology and Diagnostic Imaging)
Owen, Richard (Radiology and Diagnostic Imaging)
Department
Medical Sciences-Radiology and Diagnostic Imaging
Specialization

Date accepted
2012-05-30T15:32:58Z
Graduation date
2011-06
Degree
Master of Science
Degree level
Master's
Abstract
Background: Current vertebroplasty practices significantly vary due to differences in perceived effectiveness and safety of this interventional approach. Objectives: To assess the efficacy and safety of Percutaneous Vertebroplasty in relieving pain due to osteoporotic vertebral compression fracture. Methods: We conducted a systematic review. Randomized controlled trials were included in the efficacy review. All reports of major adverse effects were included in the safety review. We also included reports of minor adverse effects from studies of 30 consecutive cases or more. Results: Vertebroplasty had no advantage over conservative management in improving pain, disability and Health-Related Quality of Life (HR QOL), with the exception of HR-QOL at 1 month. Mortality and major adverse events following vertebroplasty are rarely reported. Conclusion: Decision to perform Percutaneous Vertebroplasty should be based on criteria that include a clear definition of conservative therapy and its failure prior to proceeding with the procedure.
Language
English
DOI
doi:10.7939/R3312W
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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