ERA

Download the full-sized PDF of Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cowsDownload the full-sized PDF

Analytics

Share

Permanent link (DOI): https://doi.org/10.7939/R3BN9XG7R

Download

Export to: EndNote  |  Zotero  |  Mendeley

Communities

This file is in the following communities:

Agricultural, Food and Nutritional Science, Department of

Collections

This file is in the following collections:

Journal Articles (Agricultural, Food and Nutritional Science)

Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cows Open Access

Descriptions

Author or creator
Dervishi, Elda
Zhang, Guanshi
Hailemariam, Dagnachew
Dunn, Suzana M.
Ametaj, Burim N.
Additional contributors
Subject/Keyword
Innate Immunity
Retained Placenta
Serum Metabolites
Transition Dairy Cows
Type of item
Journal Article (Published)
Language
English
Place
Time
Description
Background Failure to expel fetal membranes within 24 h of calving is a pathological condition defined as retained placenta (RP). The objective of this investigation was to evaluate whether there are alterations in several selected serum variables related to innate immunity and carbohydrate and lipid metabolism that precede occurrence of RP in transition Holstein dairy cows. Methods One hundred multiparous Holstein dairy cows were involved in the study. Blood samples were collected from the coccygeal vein during the −8 to +4 wks around parturition, once per week before the morning feeding. Six healthy control cows (CON) and 6 cows with RP were selected and serum samples at −8, −4, time of diagnosis of disease, and +4 wks relative to parturition were used for analyses. All samples were analyzed for lactate, non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHBA), interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor (TNF), haptoglobin (Hp), and serum amyloid A (SAA). Results Cows with RP had greater concentrations of serum lactate, IL-1, IL-6, TNF, and SAA in comparison with CON cows. Intriguingly, elevated concentrations of all five variables were observed at −8 and −4 wks before the occurrence of RP compared to healthy cows. Cows with RP also had lower DMI and milk production vs CON animals; however milk composition was not affected by RP. Conclusions Cows with RP showed an activated innate immunity 8 wks prior to diagnosis of disease. Overall results suggest that serum IL-1, IL- 6, and TNF, and lactate can be used as screening biomarkers to indicate cows that might have health issues during the transition period.
Date created
2016
DOI
doi:10.7939/R3BN9XG7R
License information

Rights
Attribution 4.0 International
Citation for previous publication
Dervishi, E., Zhang, G., Hailemariam, D., Dunn, S. M., & Ametaj, B. N. (2016). Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cows. Journal of Animal Science, and Biotechnology, 7(26), [13 pages].  http://dx.doi.org/10.1186/s40104-016-0085-9

Source

Link to related item

File Details

Date Uploaded
Date Modified
Audit Status
Audits have not yet been run on this file.
Characterization
File format: pdf (Portable Document Format)
Mime type: application/pdf
File size: 1715552
Last modified: 2017:09:06 16:11:25-06:00
Filename: BMCJASB_7_26.pdf
Original checksum: 810c8a54b9055526fc13fb142e7fed79
Well formed: true
Valid: false
Status message: Invalid destination object offset=1415720
Status message: Invalid destination object offset=1415720
Status message: Invalid destination object offset=1415720
Status message: Invalid destination object offset=1415720
Status message: Invalid destination object offset=1415720
File title: Abstract
File title: Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cows
File author: Elda Dervishi
Page count: 13
Activity of users you follow
User Activity Date