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One century later: Dissecting genetic effects for looking over old paradigms Open Access

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Author or creator
Álvarez-Castro, José M.
Yang, Rong-Cai
Additional contributors
Subject/Keyword
Environmental Effects
Mathematical Modeling
Genetic Architecture
Genetic Effects
Statistical Estimation
Type of item
Journal Article (Published)
Language
English
Place
Time
Description
Introduction: The foundation of genetics as a scientific field at the beginning of the twentieth century was not free from controversy. It meant no resolution that the advocates of the Biometric and the Mendelian schools agreed in one thing: the inheritance laws Mendel inferred by studying meristic (discrete) traits did not seem to be compatible with the findings the biometricians had been reporting for continuous (quantitative) variation since the nineteenth century (see Provine, 1971). For providing conclusive evidence against that paradigm, Fisher (1918) developed the foundations of the mathematical models of genetic effects that remain pertinent today, an endeavor in which he developed statistical tools that soon became broadly used beyond genetics.
Date created
2014
DOI
doi:10.7939/R3BC3T98Q
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Attribution 4.0 International
Citation for previous publication
Álvarez-Castro, J. M., & Yang, R. -C. (2014). One century later: Dissecting genetic effects for looking over old paradigms. Frontiers in Genetics, 5(396), [2 pages].  http://dx.doi.org/10.3389/fgene.2014.00396

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File title: One century later: dissecting genetic effects for looking over old paradigms
File author: José M. Álvarez-Castro
File author: Jos M. lvarez-Castro
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