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Permanent link (DOI): https://doi.org/10.7939/R3707X24P

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Innate immunity and carbohydrate metabolism alterations precede occurrence of subclinical mastitis in transition dairy cows Open Access

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Author or creator
Dervishi, Elda
Zhang, Guanshi
Hailemariam, Dagnachew
Dunn, Suzana M.
Ametaj, Burim N.
Additional contributors
Subject/Keyword
Blood Metabolites
Acute Phase Proteins
Subclinical Mastitis
Dairy Cows
Cytokines
Transition Period
Type of item
Journal Article (Published)
Language
English
Place
Time
Description
Background This study examined whether activation of innate immunity and alterations of carbohydrate and lipid metabolism precede development of subclinical mastitis (SCM). Methods Blood samples were collected from the coccygeal vein from 100 Holstein dairy cows at -8, -4, disease diagnosis week, and +4 weeks postpartum. Six healthy cows (controls – CON) and six cows that showed clinical signs of SCM were selected for serum analyses. All serum samples were analyzed for acute phase proteins (APP) haptoglobin (Hp) and serum amyloid A (SAA); proinflammatory cytokines including interleukin 1 (IL-1), IL-6, and tumor necrosis factor (TNF) and serum lactate, BHBA, and NEFA concentration. Data of DMI, milk production, and milk composition were recorded and analyzed. Results The results showed that cows with SCM had greater concentrations of SAA, TNF (P 
Date created
2015
DOI
doi:10.7939/R3707X24P
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Attribution 4.0 International
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Dervishi, E., Zhang, G., Hailemariam, D., Dunn, S. M., & Ametaj, B. N. (2015). Innate immunity and carbohydrate metabolism alterations precede occurrence of subclinical mastitis in transition dairy cows. Journal of Animal Science, and Technology, 57(46), [19 pages].  http://dx.doi.org/10.1186/s40781-015-0079-8

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File format: pdf (Portable Document Format)
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File title: Abstract
File title: Innate immunity and carbohydrate metabolism alterations precede occurrence of subclinical mastitis in transition dairy cows
File author: Elda Dervishi
Page count: 19
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