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Permanent link (DOI): https://doi.org/10.7939/R3VH5CS0J

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An Analysis of the Environmental Risk Factors of Childhood Asthma and Asthma-like Symptoms: Results from the National Longitudinal Survey of Children and Youth Open Access

Descriptions

Other title
Subject/Keyword
Epidemiology
Air pollution
Asthma
Hygiene hypothesis
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Parsons, Marc A
Supervisor and department
Senthilselvan, Ambikaipakan (School of Public Health)
Examining committee member and department
Beach, Jeremy (School of Public Health & Department of Medicine)
Kozyrskyj, Anita (Department of Pediatrics)
Department
School of Public Health
Specialization
Epidemiology
Date accepted
2016-03-18T15:52:28Z
Graduation date
2016-06
Degree
Master of Science
Degree level
Master's
Abstract
It is known that a multitude of environmental factors are implicated in the incidence of asthma and asthma symptoms among children; however, previous research has provided inconsistent and/or insufficient evidence as to whether residing in a farming environment during childhood can lead to a reduced asthma risk in future life as predicted by the hygiene hypothesis. Similarly, observational and laboratory studies have shown that the risk of asthma attacks in asthmatic children is related to ambient air pollution exposure in childhood, but the evidence remains ambiguous as to whether air pollution can lead to de novo childhood asthma. In this thesis, individual-level data from the National Longitudinal Study of Children and Youth (NLSCY) were used to examine the relationships between farm residence during childhood and ambient air pollution levels, respectively, with the risk of asthma and asthmatic symptoms. Children resident in farming environments were found to have a significantly lower risk of asthma incidence compared to those residing in non-rural areas in the 14-year follow-up study. Further, higher levels of nitrogen dioxide exposure (NO2) were found to be positively related with an increased 12-month prevalence of asthma attacks in childhood. These findings add to the evidence that farm residence and, to a lesser extent, ambient air pollution exposure is related to childhood asthma and its symptoms. Further research into the biological and genetic mechanisms, which may explain these findings, is needed to better understand the complex relationship between the environment and asthma risk in childhood.
Language
English
DOI
doi:10.7939/R3VH5CS0J
Rights
This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for the purpose of private, scholarly or scientific research. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.
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