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Permanent link (DOI): https://doi.org/10.7939/R3H41JN9R

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Smoking status and survival: impact on mortality of continuing to smoke one year after the angiographic diagnosis of coronary artery disease, a prospective cohort study Open Access

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Author or creator
Hammal, Fadi
Ezekowitz, Justin A.
Norris, Colleen M.
Wild, Cameron T.
Finegan, Barry A
Additional contributors
Subject/Keyword
Percutaneous coronary intervention
Coronary artery disease
Smoking cessation
Coronary artery bypass grafting
Type of item
Research Material
Language
English
Place
Time
Description
Background: Smoking is an undertreated risk factor for coronary artery disease (CAD) and is associated with adverse outcomes after myocardial infarction. Aims of our study were to determine if management of CAD by medical therapy (MT) alone or with coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) influence smoking status at one year following angiography and if a change in smoking status at one year influences long term survival. Methods: Prospective cohort study using the APPROACH registry. Two cohorts were examined: (1) 11,334 patients who returned a one year follow-up questionnaire; (2) 4,246 patients propensity-matched based on their post-angiography treatment - MT or revascularization (RV). Multivariate modeling and survival analysis were used. Results: In the propensity-matched cohort, quit rates at one year were greater among CABG patients (68%) than PCI (37%) or MT patients (47%). Smokers in the RV group, who self-reported quitting at one year, had a significantly reduced mortality compared to those who continued to smoke. Conclusions: CABG patients were more likely to quit smoking than those treated with MT alone or PCI. Quitting smoking was associated with improved long-term survival; smoking remains a key risk factor for mortality in patients with CAD. These data underscore the importance of nicotine addiction management in patients with CAD and the need to emphasize cessation particularly in those patients undergoing MT or PCI.
Date created
2014/10/20
DOI
doi:10.7939/R3H41JN9R
License information
Creative Commons Attribution-Non-Commercial-No Derivatives 3.0 Unported
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Citation for previous publication
Hammal et al. "Smoking status and survival: impact on mortality of continuing to smoke one year after the angiographic diagnosis of coronary artery disease, a prospective cohort study" BMC Cardiovascular Disorders 2014, 14:133. doi:10.1186/1471-2261-14-133
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2014-10-20T16:30:43.157+00:00
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File title: Abstract
File title: Smoking status and survival: impact on mortality of continuing to smoke one year after the angiographic diagnosis of coronary artery disease, a prospective cohort study
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