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Permanent link (DOI): https://doi.org/10.7939/R3DR2PG4D

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Preliminary Analysis of Dietary Sugar Consumption During Pregnancy Using a Potential Biomarker of Urinary Fructose Excretion Open Access

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Other title
Subject/Keyword
Pregnancy
Fructose
Urinary biomarker
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Dahlawi, Doaa H
Supervisor and department
Bell, Rhonda (Agricultural, Food, and Nutritional Science)
Examining committee member and department
Mager, Diana( Agricultural, Food, and Nutritional Science),Pediatrics, Alberta Diabetes Institute,
Vine,Donna (Agricultural, Food, and Nutritional Science)
Robson, Paula ( Research Scientist, Cancer Care, Alberta Health Services and Adjunct Associate Professor, Division of Human Nutrition, Dept of Agricultural, Food and Nutritional Science)
Department
Department of Agricultural, Food, and Nutritional Science
Specialization
Nutrition & Metabolism
Date accepted
2014-03-31T09:27:30Z
Graduation date
2014-06
Degree
Master of Science
Degree level
Master's
Abstract
A 24 hour urinary fructose excretion correlates with total sugar intakes. However, whether or not a random (“spot”) urinary fructose measurement is a reliable biomarker of fructose intake is not known. This study was done to determine the extent to which it is possible to estimate fructose intake in women using a biomarker of urinary fructose. Pregnant women were recruited from the Sweet Moms project (n=135) and provided a spot urine sample. Urinary fructose was enzymatically measured using a kit for measuring glucose and fructose. No correlation between fructose concentrations in urine sample and the fructose consumption in pregnant women. A validation study was performed on non pregnant women (n=9) after four hours to examine the validity of a urinary biomarker. Fructose excretion by non-pregnant women was positively associated with fructose ingestion. Fructose intake in pregnant women continues to be difficult to measure with currently available biomarkers.
Language
English
DOI
doi:10.7939/R3DR2PG4D
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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