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Mechanisms of Pharmacists Interventions on Medication Management and Adherence in Patients with Type 2 Diabetes Open Access


Other title
pharmacist interventions
medication management
medication adherence
Type of item
Degree grantor
University of Alberta
Author or creator
Omran, Dima
Supervisor and department
Dr. Scot Simpson (Faculty of Pharmacy and Pharmaceutical Sciences)
Examining committee member and department
Dr. Mark Makowsky (Faculty of Pharmacy and Pharmaceutical Sciences)
Dr. Lisa M. Guirguis (Faculty of Pharmacy and Pharmaceutical Sciences)
Dr. David Blackburn (College of Pharmacy and Nutrition, University of Saskatchewan)
Faculty of Pharmacy and Pharmaceutical Sciences
pharmacy practice
Date accepted
Graduation date
Master of Science
Degree level
Optimal management of type 2 diabetes requires a collaborative, team-based approach; however, the role of pharmacists on these teams has not been well-defined. In the first study of this thesis, a systematic review examined components of pharmacist interventions to improve adherence to oral antidiabetic medications. The second study was a retrospective cohort analysis to determine how the pharmacist intervention in a randomized controlled trial achieved a significant improvement in blood pressure control. The systematic review identified that pharmacist interventions to improve adherence include educational strategies combined with behavioural, affective, or provider-targeted strategies. In the cohort study, the observed improvement in blood pressure was likely due to pharmacist interventions to optimize antihypertensive medication management rather than improve medication adherence. Pharmacists can be effective additions to collaborative care teams by providing education-based interventions to improve adherence and helping to optimize medication regimens to achieve treatment targets in patients with type 2 diabetes.
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
Citation for previous publication
Omran D, Guirguis LM, Simpson SH. Systematic review of pharmacist interventions to improve adherence to oral antidiabetic medications in people with type 2 diabetes. Canadian Journal of Diabetes. 2012 October 2012;36(5):292-9

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